Results 181 to 190 of about 1,509,260 (344)

A genetic tool for the longitudinal study of a subset of post-inflammatory reactive astrocytes

, 2022
William Agnew‐Svoboda, Teresa Ubina, Zoe Figueroa, Yiu-Cheung Wong, Edward A. Vizcarra, Bryan Roebini, Emma H. Wilson, Todd A. Fiacco, Martin M. Riccomagno   +8 more
openalex   +1 more source

Chromonomer: a tool set for repairing and enhancing assembled genomes through integration of genetic maps and conserved synteny [PDF]

, 2020
Julian Catchen, Angel Amores, Susan Bassham   +2 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Editorial: Advances in genomic and genetic tools, and their applications for understanding embryonic development and human diseases. [PDF]

Front Cell Dev Biol, 2022
Abu-Elmagd M, Assidi M, Alrefaei AF, Rebai A.   +3 more
europepmc   +1 more source

Computational Tools to Aid the Design and Development of a Genetic Reference Population

, 2019
Catherine E. Welsh
openalex   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Uncovering Insights Into the Biology of Mycobacterium tuberculosis Using Genetic Tools. [PDF]

Microbiologyopen
Stamilla A, Recchia D, Stelitano G, Maci L, Marturano MC, De Rossi E, Chiarelli LR, Pasca MR, Degiacomi G.   +8 more
europepmc   +1 more source

Genetic tools for the stable overexpression of circular RNAs. [PDF]

RNA Biol, 2022
Mecozzi N, Nenci A, Vera O, Bok I, Falzone A, DeNicola GM, Karreth FA.   +6 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Understanding the Preferences of Genetic Tools and Extension Services for the Northern Australia Beef Industry. [PDF]

Animals (Basel)
Menchon P, Cosby A, Swain DL, Manning JK.   +3 more
europepmc   +1 more source