Results 11 to 20 of about 1,509,260 (344)

Computational Tools to Investigate Genetic Cardiac Channelopathies [PDF]

open access: yesFrontiers in Physiology, 2013
NA
Hugues eAbriel   +4 more
doaj   +5 more sources

A new Hoxb8FlpO mouse line for intersectional approaches to dissect developmentally defined adult sensorimotor circuits

open access: yesFrontiers in Molecular Neuroscience, 2023
Improvements in the speed and cost of expression profiling of neuronal tissues offer an unprecedented opportunity to define ever finer subgroups of neurons for functional studies.
Manon Bohic   +28 more
doaj   +1 more source

Advancing Genetic Tools in Streptococcus pneumoniae. [PDF]

open access: yesGenes (Basel), 2020
Streptococcus pneumoniae is the causative agent of a multitude of diseases, and further study into its pathogenies is vital. The pneumococcus is genetically malleable, and several tools are available to manipulate this pathogen. In this study, we attempted to utilize one such tool, the Sweet Janus cassette, to replace the capsule locus with other ...
Echlin H, Rosch JW.
europepmc   +4 more sources

Modern Approaches for the Genetic Improvement of Rice, Wheat and Maize for Abiotic Constraints-Related Traits: A Comparative Overview

open access: yesAgronomy, 2021
After a basic description of the different sets of genetic tools and genomic approaches most relevant for modern crop breeding (e. g., QTL mapping, GWAS and genomic selection; transcriptomics, qPCR and RNA-seq; transgenesis and gene editing), this review
Elena Benavente, Estela Giménez
doaj   +1 more source

Precision genetics tools for genetic improvement of banana

open access: yesThe Plant Genome, 2023
Abstract Banana is an important food security crop for millions of people in the tropics but it faces challenges from diseases and pests. Traditional breeding methods have limitations, prompting the exploration of precision genetic tools like genetic modification and genome editing.
Jaindra Nath Tripathi   +2 more
openaire   +3 more sources

Transgene-free genome editing and RNAi ectopic application in fruit trees: Potential and limitations

open access: yesFrontiers in Plant Science, 2022
For the past fifteen years, significant research advances in sequencing technology have led to a substantial increase in fruit tree genomic resources and databases with a massive number of OMICS datasets (transcriptomic, proteomics, metabolomics ...
Satyanarayana Gouthu   +4 more
doaj   +1 more source

Construction and Application of a Plasmid-Based Signal Peptide Library for Improved Secretion of Recombinant Proteins with Priestia megaterium

open access: yesMicroorganisms, 2022
The secretion of recombinant proteins plays an important role in their economic production and purification. The secretion efficiency depends on the responsible signal peptide (SP) in combination with the target protein and the given host and cannot be ...
Janine Mayer   +6 more
doaj   +1 more source

An integrated molecular and conventional breeding scheme for enhancing genetic gain in maize in Africa [PDF]

open access: yes, 2020
Open Access Journal; Published online: 06 Nov 2019Maize production in West and Central Africa (WCA) is constrained by a wide range of interacting stresses that keep productivity below potential yields.
Gedil, M., Menkir, A.
core   +1 more source

A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila

open access: yeseLife, 2020
Genetic screens are powerful tools for the functional annotation of genomes. In the context of multicellular organisms, interrogation of gene function is greatly facilitated by methods that allow spatial and temporal control of gene abrogation.
Fillip Port   +18 more
doaj   +1 more source

Mix and Match: Promoters and Terminators for Tuning Gene Expression in the Methylotrophic Yeast Ogataea polymorpha

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
The yeast Ogataea polymorpha is an upcoming host for bio-manufacturing due to its unique physiological properties, including its broad substrate spectrum, and particularly its ability to utilize methanol as the sole carbon and energy source.
Katrin Wefelmeier   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy