Results 21 to 30 of about 733,956 (256)
CRISPR (clustered regularly interspaced short palindromic repeats)-Cas systems are widely distributed among bacteria and archaea. In this study, we demonstrate the successful utilization of the type I-D CRISPR-Cas system for genetic engineering in the ...
Jan Bost +5 more
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The GenoChip: A New Tool for Genetic Anthropology [PDF]
The Genographic Project is an international effort aimed at charting human migratory history. The project is nonprofit and nonmedical, and, through its Legacy Fund, supports locally led efforts to preserve indigenous and traditional cultures. Although the first phase of the project was focused on uniparentally inherited markers on the Y-chromosome and ...
Elhaik E +53 more
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The thermophilic archaeon Sulfolobus acidocaldarius can use different carbon sources for growth, including the pentoses D-xylose and L-arabinose. In this study, we identified the activator XylR (saci_2116) responsible for the transcriptional regulation ...
Nienke van der Kolk +7 more
doaj +1 more source
Tools for the genetic manipulation of Herpetomonas muscarum [PDF]
Abstract Trypanosomatid parasites are causative agents of important human and animal diseases such as sleeping sickness and leishmaniasis. Most trypanosomatids are transmitted to their mammalian hosts by insects, often belonging to Diptera (or true flies).
Sloan, MA, Ligoxygakis, P
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Simple Expression Domains Are Regulated by Discrete CRMs During Drosophila Oogenesis
Eggshell patterning has been extensively studied in Drosophila melanogaster. However, the cis-regulatory modules (CRMs), which control spatiotemporal expression of these patterns, are vastly unexplored.
Nicole T. Revaitis +5 more
doaj +1 more source
Synthetic biology in marine cyanobacteria: Advances and challenges
The current economic and environmental context requests an accelerating development of sustainable alternatives for the production of various target compounds.
Barbara Bourgade, Karin Stensjö
doaj +1 more source
Development of a pan-neuronal genetic driver in Aedes aegypti mosquitoes
Summary: The recent development of neurogenetic tools in Aedes aegypti mosquitoes is beginning to shed light on the neural basis of behaviors that make this species a major vector of human disease.
Zhilei Zhao +2 more
doaj +1 more source
Virus as Renal Functional Genetic Tools [PDF]
Viral vectors enable efficient transfection of ectopic DNA into hard to transfect cells. Viral vectors are normally used to obtain permanent modification of target cells, and tissues expect for the cases where integrase-deficient viruses are used.
Sharma Abhishek Kumar +1 more
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Optimized Replication of Arrayed Bacterial Mutant Libraries Increases Access to Biological Resources
Biological collections, including arrayed libraries of single transposon (Tn) or deletion mutants, greatly accelerate the pace of bacterial genetic research.
Julia L. E. Willett +5 more
doaj +1 more source
Genetic elements of plant viruses as tools for genetic engineering [PDF]
Viruses have developed successful strategies for propagation at the expense of their host cells. Efficient gene expression, genome multiplication, and invasion of the host are enabled by virus-encoded genetic elements, many of which are well characterized. Sequences derived from plant DNA and RNA viruses can be used to control expression of other genes
A R, Mushegian, R J, Shepherd
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