Results 221 to 230 of about 1,509,260 (344)

Establishment of genetic tools for genomic DNA engineering of Halomonas sp. KM-1, a bacterium with potential for biochemical production. [PDF]

Microb Cell Fact, 2022
Tsuji A, Takei Y, Azuma Y.
europepmc   +1 more source

Genetic Diversity Analysis Using Molecular and Genomic Tools

Priyadarshini Sanjay Borale1*
openalex   +1 more source

Postmortem Genetic Testing Is an Increasingly Utilized Tool in Death Investigation

, 2022
Rebecca Latimer, Heather MacLeod, Lisa Dellefave‐Castillo, Daniela Macaya, Tara R. Hart   +4 more
openalex   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Optimized genetic tools for neuroanatomical and functional mapping of the Aedes aegypti olfactory system. [PDF]

G3 (Bethesda)
Shankar S, Giraldo D, Tauxe GM, Spikol ED, Li M, Akbari OS, Wohl MP, McMeniman CJ.   +7 more
europepmc   +1 more source

New Platform for Screening Genetic Libraries at Elevated Temperatures: Biological and Genomic Information and Genetic Tools of Geobacillus thermodenitrificans K1041. [PDF]

Appl Environ Microbiol, 2022
Koyama K, Mikawa Y, Nakagawa S, Kurashiki R, Ohshiro T, Suzuki H.   +5 more
europepmc   +1 more source

Finite Element Method Coupled with Genetic Algorithm as a Design Optimization Tool of Electromagnetic Devices [PDF]

, 2004
Лидија Петковска, Goga Cvetkovski, Vasilija Šarac   +2 more
openalex  

In silico identification of genetic variants in glucocerebrosidase (GBA) gene involved in Gaucher's disease using multiple software tools [PDF]

, 2014
Madhumathi Manickam, Palaniyandi Ravanan, Pratibha Singh, Priti Talwar   +3 more
openalex   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Genetic tools that target mechanoreceptors produce reliable labeling of bladder afferents and altered mechanosensation. [PDF]

Am J Physiol Renal Physiol
Tran EL, Stuedemann SA, Ridlon M, Link OD, Keil Stietz KP, Crawford LK.   +5 more
europepmc   +1 more source