Results 241 to 250 of about 1,520,984 (293)
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Genetic tools for engineering hyperthermophiles.
Genetic tools for engineering hyperthermophiles.openaire
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Advanced genetic tools for plant biotechnology
Nature Reviews Genetics, 2013Basic research has provided a much better understanding of the genetic networks and regulatory hierarchies in plants. To meet the challenges of agriculture, we must be able to rapidly translate this knowledge into generating improved plants. Therefore, in this Review, we discuss advanced tools that are currently available for use in plant biotechnology
Wusheng, Liu +2 more
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Genetic tools for cyanobacteria
Applied Microbiology and Biotechnology, 2002Cyanobacteria are oxygenic photosynthetic bacteria that have been used increasingly to study diverse biological processes, including photosynthesis and its regulation; cell differentiation and N2 fixation; metabolism of nitrogen, carbon, and hydrogen; resistance to environmental stresses; and molecular evolution.
O A, Koksharova, C P, Wolk
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Proceedings 20th International Conference of the Chilean Computer Science Society, 2002
Knowledge discovery is the most desirable end product of an enterprise information system. Research from different areas recognizes that a new generation of intelligent tools for automated data mining is needed to deal with large databases. In this sense, induction based learning systems have emerged as a promising approach.
A.R. Pozo, M. Hasse
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Knowledge discovery is the most desirable end product of an enterprise information system. Research from different areas recognizes that a new generation of intelligent tools for automated data mining is needed to deal with large databases. In this sense, induction based learning systems have emerged as a promising approach.
A.R. Pozo, M. Hasse
openaire +1 more source
Genetic Tools from Nature and the Nature of Genetic Tools
Crop Science, 2006The opportunity to apply genetics to the improvement of crops is greater now than any time in history. Agricultural advancements will depend even more on genetics in the future as we try to produce more food, while being in harmony with the environment.
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Genetic Algorithms-a Tool for OR?
Journal of the Operational Research Society, 1996Summary: Compared with other metaheuristic techniques such as simulated annealing and tabu search, research into the use of genetic algorithms for the solution of OR problems is still in its infancy. This paper provides an introduction to genetic algorithms and their use in the solution of both classical and practical operational research problems ...
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Molecular Ophthalmic Genetics Tools
Acta Ophthalmologica, 2011AbstractPurpose To provide an overview of recent developments in molecular genetic tools applied in ocular genetics.Methods Genomewide strategies for copy number screening (arrayCGH), identity‐by‐descent (IBD) mapping and massive parallel sequencing (MPS) or next‐generation sequencing (NGS) technologies (targeted resequencing, whole exome and genome ...
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1984
In the past ten years several advances in biotechnology have revolutionized the way fundamental biological problems are approached. I will discuss three of these relatively recently developed disciplines in biotechnology—recombinant DNA, microchemical instrumentation, and monoclonal antibodies—and I will point out the striking synergies that arise from
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In the past ten years several advances in biotechnology have revolutionized the way fundamental biological problems are approached. I will discuss three of these relatively recently developed disciplines in biotechnology—recombinant DNA, microchemical instrumentation, and monoclonal antibodies—and I will point out the striking synergies that arise from
openaire +2 more sources