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Computational Tools for Causal Inference in Genetics
Cold Spring Harbor Perspectives in Medicine, 2020The advent of large-scale, phenotypically rich, and readily accessible data provides an unprecedented opportunity for epidemiologists, statistical geneticists, bioinformaticians, and also behavioral and social scientists to investigate the causes and consequences of disease. Computational tools and resources are an integral component of such endeavors,
Tom G, Richardson +2 more
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Transposable Bacteriophages as Genetic Tools
2017Phage Mu is the paradigm of a growing family of bacteriophages that infect a wide range of bacterial species and replicate their genome by replicative transposition. This molecular process, which is used by other mobile genetic elements to move within genomes, involves the profound rearrangement of the host genome [chromosome(s) and plasmid(s)] and can
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RNA Interference as a Genetic Tool in Trypanosomes
2008RNA interference (RNAi) is a cellular mechanism that is often exploited as a technique for quelling the expression of a specific gene. RNAi studies are carried out in vivo, making this a powerful means for the study of protein function in situ Several trypanosomatids, including those organisms responsible for human and animal diseases, naturally ...
Vivian, Bellofatto +1 more
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Population Genetic Tools: Application to Cancer
Seminars in Oncology, 2007The availability of a reference human genome sequence, an increasingly dense catalog, knowledge of common genetic variation, and new developments in technology present an unprecedented opportunity to systematically explore the genetic basis of complex human diseases such as cancer.
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Self‐Insurance With Genetic Testing Tools
Journal of Risk and Insurance, 2015AbstractThe development of genetic testing creates opportunities to better target disease prevention actions. In this article, we determine how the genetic information modifies self‐insurance efforts in different health insurance market equilibria with adverse selection.
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Genetic Assembly Tools for Synthetic Biology
2011With the completion of myriad genome sequencing projects, genetic bioengineering has expanded into many applications including the integrated analysis of complex pathways, the construction of new biological parts and the redesign of existing, natural biological systems.
Billyana, Tsvetanova +11 more
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Genetic Testing in Prostate Cancer Management: Considerations Informing Primary Care
Ca-A Cancer Journal for Clinicians, 2022Todd M Morgan +2 more
exaly
GENETICS AS A TOOL IN ALCOHOL RESEARCH
Annals of the New York Academy of Sciences, 1972openaire +2 more sources