Results 21 to 30 of about 1,509,260 (344)
Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons
eLife, 2022 Auxin-inducible degrons are a chemical genetic tool for targeted protein degradation and are widely used to study protein function in cultured mammalian cells.
Lewis Macdonald +8 more
doaj +1 more source
Frontiers in Microbiology, 2023 CRISPR (clustered regularly interspaced short palindromic repeats)-Cas systems are widely distributed among bacteria and archaea. In this study, we demonstrate the successful utilization of the type I-D CRISPR-Cas system for genetic engineering in the ...
Jan Bost +5 more
doaj +1 more source
Development of Genetic Modification Tools for Hanseniasporauvarum [PDF]
International Journal of Molecular Sciences, 2021 Apiculate yeasts belonging to the genus Hanseniaspora are commonly isolated from viticultural settings and often dominate the initial stages of grape must fermentations. Although considered spoilage yeasts, they are now increasingly becoming the focus of research, with several whole-genome sequencing studies published in recent years.
Jennifer Badura +6 more
openaire +2 more sources
Frontiers in Microbiology, 2020 The thermophilic archaeon Sulfolobus acidocaldarius can use different carbon sources for growth, including the pentoses D-xylose and L-arabinose. In this study, we identified the activator XylR (saci_2116) responsible for the transcriptional regulation ...
Nienke van der Kolk +7 more
doaj +1 more source
Genetic algorithm based two-mode clustering of metabolomics data [PDF]
, 2008 Metabolomics and other omics tools are generally characterized by large data sets with many variables obtained under different environmental conditions.
Berg, R.A., van den +4 more
core +3 more sources
Virus as Renal Functional Genetic Tools [PDF]
, 2019 Viral vectors enable efficient transfection of ectopic DNA into hard to transfect cells. Viral vectors are normally used to obtain permanent modification of target cells, and tissues expect for the cases where integrase-deficient viruses are used.
Sharma Abhishek Kumar +1 more
openaire +3 more sources
Molecular epidemiology of African sleeping sickness [PDF]
, 2009 Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically give ...
A. TAIT +5 more
core +2 more sources
Plant genetic reseources: effective utilization [PDF]
, 2010 Characterizing better understanding the genome organization and differentiating identity of genotypes based on their morphology and genome characteristics are vital determinants in their commercialization, management of germplasm repositories, and ...
Budak, Hikmet
core +1 more source
Novel genetic tools for Hansenula polymorpha [PDF]
FEMS Yeast Research, 2011 Hansenula polymorpha is an important yeast in industrial biotechnology. In addition, it is extensively used in fundamental research devoted to unravel the principles of peroxisome biology and nitrate assimilation. Here we present an overview of key components of the genetic toolbox for H. polymorpha.
Ruchi, Saraya +5 more
openaire +2 more sources
Genetic issues in the diagnosis of dystonias [PDF]
, 2013 Dystonias are heterogeneous hyperkinetic movement disorders characterized by involuntary muscle contractions which result in twisting and repetitive movements and abnormal postures.
Petrucci S., Valente E. M.
core +1 more source