Results 141 to 150 of about 1,032,830 (329)

Robust genetic transformation of sorghum (Sorghum bicolor L.) using differentiating embryogenic callus induced from immature embryos [PDF]

, 2017
Srinivas Belide, Thomas Vanhercke, James R. Petrie, Surinder Singh   +3 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Agrobacterium-mediated transformation of Citrus sinensis and Citrus limonia epicotyl segments

Scientia Agricola, 2003
Genetic transformation allows the release of improved cultivars with desirable characteristics in a shorter period of time and therefore may be useful in citrus breeding programs.
Weliton Antonio Bastos de Almeida, Francisco de Assis Alves Mourão Filho, Beatriz Madalena Januzzi Mendes, Alexandra Pavan, Adriana Pinheiro Martinelli Rodriguez   +4 more
doaj  

Tapping into the Potential of Underutilized Niger (Guizotia abyssinica (L. f.) Cass.) Through Breeding and Biotechnological Tools

Agriculture
Niger (Guizotia abyssinica (L. f.) Cass.), an oilseed crop from the Compositae family, thrives in temperate and tropical climates. Its small seeds, rich in oil (50–60% biocrude), are widely used for biodiesel, soap production, and as a condiment in ...
Jayashri Narayan Papade, Krishnananda Pralhad Ingle, Niranjan Ravindra Thakur, Sunil Shriram Gomashe, Munagapati Padmavathy, Stanislaus Antony Ceasar   +5 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Preliminary Establishment of an Efficient Regeneration and Genetic Transformation System for Hemerocallis middendorffii Trautv. & C. A. Mey.

Horticulturae
Hemerocallis middendorffii is widely used in the landscaping of Northern China for its exceptional ornamental and ecological attributes. It is also the focus of a substantial body of germplasm development and stress tolerance research.
Jinxue Du, Jingbo Shi, Nan Zhang, Yingzhu Liu, Wei Liu   +4 more
doaj   +1 more source

Agrobacterium-mediated genetic transformation of Populus deltoides marsh clone G48 with gus and npt-II genes

, 2016
Abir Saraswat, Khan Aa, A. K. Thakur, Anupama Gaur, DK Srivastava   +4 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Current Advances in the Functional Genes of Edible and Medicinal Fungi: Research Techniques, Functional Analysis, and Prospects

Journal of Fungi
Functional genes encode various biological functions required for the life activities of organisms. By analyzing the functional genes of edible and medicinal fungi, varieties of edible and medicinal fungi can be improved to enhance their agronomic traits,
Wenyun Li, Gen Zou, Dapeng Bao, Yingying Wu   +3 more
doaj   +1 more source