Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Genetic Transformation of Neisseria gonorrhoeae to Streptomycin Resistance [PDF]
, 1966 P. Frederick Sparling
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Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Agrobacterium-mediated transformation of Citrus sinensis and Citrus limonia epicotyl segments
Scientia Agricola, 2003 Genetic transformation allows the release of improved cultivars with desirable characteristics in a shorter period of time and therefore may be useful in citrus breeding programs.
Weliton Antonio Bastos de Almeida +4 more
doaj
BIOCHEMICAL AND GENETIC STUDIES OF INTEGRATION AND RECOMBINATION IN BACILLUS SUBTILIS TRANSFORMATION [PDF]
, 1964 Walter F. Bodmer, A. T. Ganesan
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Automatic Construction of Accurate Image Processing using AdaBoost [PDF]
, 2009 Image processing and recognition technologies are required to solve various problems. We have already proposed the system which automatically constructs image processing with Genetic Programming (GP), Automatic Construction of Tree-structural Image ...
Ando, Jun, Nagao, Tomoharu
core
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
LINKAGE OF GENETIC UNITS OF BACILLUS SUBTILIS IN DNA TRANSFORMATION [PDF]
, 1961 Eugene W. Nester, Joshua Lederberg
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Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
GENETIC TRANSFORMATION OF RHIZOBIUM : A REVIEW OF THE WORK OF R. BALASSA [PDF]
, 1963 G. Balassa
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