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Genetic Transformation of Candida albicans
2009Genetic transformation is the primary method of genetic manipulation of Candida albicans. The lack of a complete sexual cycle prevents application of classical genetic analyses. However, transformation permits introduction into the genome of a wide variety of defined mutations including deletions, insertions, and fusions.
Ana M, Ramon, William A, Fonzi
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Molecular Mechanisms in Genetic Transformation
1977Molecular mechanisms of recombination of genetic material are most readily studied in microorganisms; a great deal is known about recombination of transforming DNA, introduced into the cell from the medium, with DNA inside bacteria. At present it is doubtful that this type of transformation will be of use in improving crop plants.
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