Results 291 to 300 of about 6,473,238 (362)

Etiologies of patients with adult-onset epilepsy over the past 25 years: a retrospective study in China. [PDF]

BMC Neurol
Zhang X, Wang Z, Xiang F, Li Y, Shi X, Shao C, Lang S, Wang X.   +7 more
europepmc   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Genetic response and metabolic adaptation to partial-record selection for egg production in Dokki-4 laying hens. [PDF]

Sci Rep
Semida DAM, Emam AM, Mahmoud BYF, ElFull EA, Shalaby MS, Abou Khadiga G.   +5 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Differential results of genetic risk scoring for multiple sclerosis in European and African American populations. [PDF]

Mult Scler
Rivier CA, Xu L, Clocchiatti-Tuozzo S, Zhao H, Ohno-Machado L, Hafler DA, Falcone GJ, Longbrake EE.   +7 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Assessing the Reliability of Automatic Milking Systems Data to Support Genetic Improvement in Dairy Cattle. [PDF]

Animals (Basel)
Ponzo E, Moretti R, Masia F, Vrieze E, Sacchi P, Chessa S.   +5 more
europepmc   +1 more source

Integrating Bibliometrics and Bioinformatics to Map Knowledge Structure, Trends, and Genetic Insights in Polycystic Ovary Syndrome and Tumors (2015–2024)

Meng Liu, Ying Xiong, Shaohua Zhang, Jun Yuan, Zhiqiang Cheng   +4 more
openalex   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source