Results 131 to 140 of about 1,291,194 (313)

Genetic variability, correlation and path analysis inAshwagandha [Withania somnifera (L.) Dunal] [PDF]

open access: yesElectronic Journal of Plant Breeding, 2014
Forty diverse genotypes of Ashwagandha [Withania somnifera (L.)Dunal] were evaluated for 12 quantitative characters. Higher magnitude of genotypic and phenotypic coefficient of variation was recorded for leaf width, number of primary branches per plant ...
Nilesh R. Joshi, M. A. Patel, K.N. Prajapati and A. D. Patel
doaj  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Evolutionary associations between sand seatrout (Cynoscion arenarius) and silver seatrout (C. nothus) inferred from morphological characters, mitochondrial DNA, and microsatellite markers [PDF]

open access: yes, 2009
The evolutionary associations between closely related fish species, both contemporary and historical, are frequently assessed by using molecular markers, such as microsatellites.
Anderson, Joel D.   +3 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Genetic analysis and qtl mapping of agro-morphological traits in lowland rice (Oryza sativa L.) under drought conditions [PDF]

open access: yes, 2016
The present study was undertaken to evaluate lowland rice genetic variability associated with agro-morphological traits under drought condition. A set of 250 recombinant inbred lines (RILs) from the cross between rice parental cultivarIR64 (sensitive to ...
Audebert, Alain   +6 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

GENETIC DIVERSITY ANALYSIS OF MANGABA (Hancornia speciosa Gomes), AN EXOTIC BRAZILIAN TROPICAL SPECIES

open access: yesTropical and Subtropical Agroecosystems, 2012
Twenty genotypes from natural population of mangaba located in Itaporanga D’Ajuda (Sergipe state - Brazil) were subjected to analysis using RAPD markers.
Ana Veruska Cruz da Silva   +4 more
doaj  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Evolutionary Fitness in Variable Environments

open access: yes, 2015
One essential ingredient of evolutionary theory is the concept of fitness as a measure for a species' success in its living conditions. Here, we quantify the effect of environmental fluctuations onto fitness by analytical calculations on a general ...
Melbinger, Anna, Vergassola, Massimo
core  

Home - About - Disclaimer - Privacy