Results 81 to 90 of about 668,410 (314)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Genetic divergence, heritability and genetic advance in mutant lines of urdbean [Vigna mungo (L.) Hepper]

open access: yes, 2017
Twenty six mutant lines of urdbean [Vigna mungo (L) Hepper] were analyzed for genetic diversity using Mahalanobis D2 statistics. Based on twelve important agronomic characters, the genotypes were grouped into 4 clusters.
Urdbean .   +3 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Genetic variability in parasites and host-parasite interactions

open access: yes, 1996
We have examined genetic variability in parasites in the context of ecological interactions with the host. Recent research on Echinococcus, Giardia and Cryptosporidium has been used to illustrate: (i) the problems that parasite variability and species ...
Thompson, R.C.A., Lymbery, A.J.
core  

Genetic Variability of Polypedilum (Diptera: Chironomidae) from Southwest Ecuador

open access: yes, 2022
Chironomids show a wide distribution and can occupy several habitats due to their high adaptive capacity in different freshwater environments. The genus Polypedilum is found along a wide elevational and environmental gradient in the neotropics, and its ...
Prat, Narcís   +13 more
core   +1 more source

Increased Resting Heart Rate and Genetic Variability

open access: yesCentral Asian Journal of Medical Sciences, 2019
No abstract in ...
Bayasgalan Gombojav   +1 more
doaj   +1 more source

Antigenic and Genetic Variability of Human Metapneumoviruses

open access: yesEmerging Infectious Diseases, 2004
Human metapneumovirus (HMPV) is a member of the subfamily Pneumovirinae within the family Paramyxo- viridae. Other members of this subfamily, respiratory syncytial virus and avian pneumovirus, can be divided into subgroups on the basis of genetic or antigenic differences or both.
van den Hoogen, BG   +7 more
openaire   +4 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Global amphibian declines, loss of genetic diversity and fitness: a review

open access: yes, 2010
It is well established that a decrease in genetic variation can lead to reduced fitness and lack of adaptability to a changing environment. Amphibians are declining on a global scale, and we present a four-point argument as to why this taxonomic group ...
Allentoft, M.E.   +5 more
core   +1 more source

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