Results 101 to 110 of about 1,291,194 (313)

Genetic studies in pigeonpea (Cajanus cajan (L.) Mill sp) [PDF]

open access: yesElectronic Journal of Plant Breeding, 2011
Study was carried out for genetic variability, heritability and genetic advance of twelve characters in fifty white seed coated lines.High coefficient of variation for number of pods, seed yield per plant, plant height and raceme length and high values ...
D.Bhadru
doaj  

The Parasite that Causes Whirling Disease, \u3cem\u3eMyxobolus cerebralis\u3c/em\u3e, is Genetically Variable Within and Across Spatial Scales [PDF]

open access: yes, 2012
Understanding the genetic structure of parasite populations on the natural landscape can reveal important aspects of disease ecology and epidemiology and can indicate parasite dispersal across the landscape.
Kerans, Billie L.   +2 more
core   +1 more source

Environmental variables, habitat discontinuity and life history shaping the genetic structure of Pomatoschistus marmoratus [PDF]

open access: yes, 2014
Coastal lagoons are semi-isolated ecosystems exposed to wide fluctuations of environmental conditions and showing habitat fragmentation. These features may play an important role in separating species into different populations, even at small spatial
A Pérez-Ruzafa   +119 more
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

SSR-Based genetic variability assessment of Tunisian local citrus rootstocks : [P22] [PDF]

open access: yes, 2008
In the framework of the 6th PCRD European Project 'CIBEWU', the genetic diversity of Tunisian Citrus rootstocks germplasm was assessed using microsatellite markers (SSR).
Belfalah, Zina   +4 more
core  

Apeced in Turkey: a case report and insights on genetic and phenotypic variability [PDF]

open access: yes, 2018
APECED is a rare monogenic recessive disorder caused by mutations in the AIRE gene. In this manuscript, we report a male Turkish patient with APECED syndrome who presented with chronic mucocutaneous candidiasis associated with other autoimmune ...
Alessandra Fierabraccia   +4 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Novel homozygous GBA2 mutation in a patient with complicated spastic paraplegia [PDF]

open access: yes, 2018
Hereditary spastic paraplegias (HSPs) are a heterogeneous group of neurological disorders characterized primarily by a pyramidal syndrome with lower limb spasticity, which can manifest as pure HSP or associated with a number of neurological or non ...
Bertini, Enrico   +10 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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