Results 51 to 60 of about 233,443 (255)

Gene Flow, Effective Population Sizes, and Genetic Variance Components in Birds [PDF]

open access: yesEvolution, 1980
The genetic structure of natural populations is of general interest because many current models in ecology and evolution involve assumptions about the viscosity of breeding populations. For instance, theories of group and kinship selection, local adaptation, and speciation all depend on the magnitude of an among-deme component of genetic variance.
openaire   +2 more sources

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman   +17 more
wiley   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

Genetic components of birth weight of texel sheep reared in extensive system

open access: yesActa Scientiarum: Animal Sciences, 2017
This study aimed to estimate the components of (co)variance, genetic and phenotypic parameters and trends for birth weight. We used 783 birth weight records, between 2012 to 2016, of Texel sheep reared in extensive system.
Fernando Amarilho-Silveira   +5 more
doaj   +1 more source

Using the realized relationship matrix to disentangle confounding factors for the estimation of genetic variance components of complex traits

open access: yesGenetics Selection Evolution, 2010
Background In the analysis of complex traits, genetic effects can be confounded with non-genetic effects, especially when using full-sib families. Dominance and epistatic effects are typically confounded with additive genetic and non-genetic effects ...
Visscher Peter M   +3 more
doaj   +1 more source

Genetic variance of sunflower yield components - Heliantus annuus L.

open access: yesGenetika, 2003
The main goals of sunflower breeding in Yugoslavia and abroad are increased seed yield and oil content per unit area and increased resistance to diseases, insects and stress conditions via an optimization of plant architecture. In order to determine the mode of inheritance, gene effects and correlations of total leaf number per plant, total leaf area ...
Hladni, Nada   +2 more
openaire   +2 more sources

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig   +13 more
wiley   +1 more source

Estimates of heritability and genetic correlations for milk coagulation properties and individual laboratory cheese yield in Sarda ewes

open access: yesAnimal, 2017
Objective of this study was to estimate genetic parameters of milk coagulation properties (MCPs) and individual laboratory cheese yield (ILCY) in a sample of 1018 Sarda breed ewes farmed in 47 flocks. Rennet coagulation time (RCT), curd-firming time (k20)
A. Puledda   +7 more
doaj   +1 more source

Treatment Decision‐Making Roles and Preferences Among Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Decision‐making (DM) dynamics between adolescents and young adults (AYAs) with cancer, parents, and oncologists remain underexplored in diverse populations. We examined cancer treatment DM preferences among an ethnically and socioeconomically diverse group of AYAs and their parents.
Amanda M. Gutierrez   +14 more
wiley   +1 more source

Genomic prediction with non-additive effects in beef cattle: stability of variance component and genetic effect estimates against population size

open access: yesBMC Genomics, 2021
Background Genomic prediction is now an essential technology for genetic improvement in animal and plant breeding. Whereas emphasis has been placed on predicting the breeding values, the prediction of non-additive genetic effects has also been of ...
Akio Onogi   +4 more
doaj   +1 more source

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