Results 131 to 140 of about 649,887 (338)

A Rare Genetically Determined Variant of Pseudocholinesterase in two German Families with High Plasma Enzyme Activity [PDF]

, 1979
Axel Delbrück, E. Henkel
openalex   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Genetic variants in an acetylcholine receptor from drosophila melanogaster [PDF]

, 1978
Linda M. Hall, Reid W. Von Borstel, Barbara C Osmond, Sydney D. Hoeltzli, Thomas H. Hudson   +4 more
openalex   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

NPM1 GENETIC VARIANTS: THE IMPORTANCE IN THE DIAGNOSIS OF THE ACUTE MYELOID LEUKEMIA

Hematology, Transfusion and Cell Therapy, 2023
Background: Acute Myeloid Leukemia a severe cancer of the bone marrow (BM), characterized by accumulation of leukemic blasts in the BM and peripheral blood.
doaj  

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source

The frequency in Japanese of genetic variants of 22 proteins: IV. Acid phosphatase, NADP‐isocitrate dehydrogenase, peptidase A, peptidase B and phosphohexose isomerase [PDF]

, 1978
Robert J. Tanis, Naoyasu Ueda, C Satoh, R E Ferrell, S Kishimoto, J.V. Neel, Howard B. Hamilton, N. Ohno   +7 more
openalex   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

HUMAN CHOLINESTERASE (PSEUDOCHOLINESTERASE): GENETIC VARIANTS AND THEIR RECOGNITION

, 1969
H. Lehmann, J. Liddell
openalex   +1 more source

Genetic Variants of von Willebrand's Disease [PDF]

, 1972
Lars Holmberg, I. M. Nilsson
openalex   +1 more source