Results 121 to 130 of about 2,029,300 (329)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Genetics and Molecular Biology, 2011 In Greece, seven native horse breeds have been identified so far. Among these, the Skyros pony is outstanding through having a distinct phenotype. In the present study, the aim was to assess genetic diversity in this breed, by using different types of ...
Elisabeth Bömcke +2 more
doaj
Annals of Hepatology, 2012 Introduction. The treatment of hepatitis C virus (HCV) genotype 1 with ribavirin (RBV) and pegylated-interferon alpha (peg-IFNα) provides a low-level sustained virological response (SVR).
Laura E. Martínez-Gómez +8 more
doaj +1 more source
Transcriptional plasticity buffers genetic variation in zinc homeostasis [PDF]
, 2019 Alice Pita-Barbosa +4 more
openalex +1 more source
Genetic variations among the isolates of Bipolaris Maydis based on phenotypic and molecular markers [PDF]
, 2021 Azra Nadeem +8 more
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Genetic variation between Colletotrichum lindemuthianum isolates
Plant Protection Science, 2002 We characterized the genetic diversity of seventy-three C. lindemuthianum isolates collected from 10 different countries by Amplified Fragment Length Polymorphism (AFLP) analysis.
K.I. Ansari +5 more
doaj +1 more source
Sample genealogies and genetic variation in populations of variable size
, 2009 We consider neutral evolution of a large population subject to changes in its population size. For a population with a time-variable carrying capacity we have computed the distributions of the total branch lengths of its sample genealogies.
Eriksson, A. +3 more
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Copy Number Variation in Fungi and Its Implications for Wine Yeast Genetic Diversity and Adaptation [PDF]
, 2018 Jacob L. Steenwyk, Antonis Rokas
openalex +1 more source