Translational regulation contributes to the elevated CO2 response in two Solanum species. [PDF]
Understanding the impact of elevated CO2 (eCO2 ) in global agriculture is important given climate change projections. Breeding climate-resilient crops depends on genetic variation within naturally varying populations.
Brady, Siobhan M+6 more
core +2 more sources
The effect of genomic information on optimal contribution selection in livestock breeding programs [PDF]
BACKGROUND: Long-term benefits in animal breeding programs require that increases in genetic merit be balanced with the need to maintain diversity (lost due to inbreeding). This can be achieved by using optimal contribution selection. The availability of
Clark, Samuel A+3 more
core +6 more sources
Visualizing genetic constraints [PDF]
Principal Components Analysis (PCA) is a common way to study the sources of variation in a high-dimensional data set. Typically, the leading principal components are used to understand the variation in the data or to reduce the dimension of the data for ...
Gaydos, Travis L.+6 more
core +3 more sources
Ironing out the details: Untangling dietary iron and genetic background in diabetes [PDF]
The search for genetic risk factors in type-II diabetes has been hindered by a failure to consider dietary variables. Dietary nutrients impact metabolic disease risk and severity and are essential to maintaining metabolic health.
Lawson, Heather A, Miranda, Mario A
core +2 more sources
Genetic variation in Cumbrians
Regional variation in the genetic constitution of the Cumbrian population is demonstrated in a survey of blood groups, red cell enzymes, and secretor status in a large sample of schoolchildren. In particular, the south and centre appear to be distinct from the remainder of Cumbria, but in different directions. The features of the central Lake District,
R.J. Mitchell+3 more
openaire +3 more sources
A global reference for human genetic variation [PDF]
The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report completion of the project, having reconstructed the genomes of 2,504 individuals from 26 populations using a combination of low-coverage ...
Colonna V Genomes Project Consortium Adam Auton+280 more
openaire +18 more sources
Oracle selection provides insight into how far off practice is from Utopia in plant breeding
Since the introduction of genomic selection in plant breeding, high genetic gains have been realized in different plant breeding programs. Various methods based on genomic estimated breeding values (GEBVs) for selecting parental lines that maximize the ...
David Vanavermaete+3 more
doaj +1 more source
The Genetic Basis of Mutation Rate Variation in Yeast. [PDF]
Mutations are the root source of genetic variation and underlie the process of evolution. Although the rates at which mutations occur vary considerably between species, little is known about differences within species, or the genetic and molecular basis ...
Bloom, Joshua S+2 more
core +1 more source
Molecular Genetic Influences on Normative and Problematic Alcohol Use in a Population-Based Sample of College Students [PDF]
Background: Genetic factors impact alcohol use behaviors and these factors may become increasingly evident during emerging adulthood. Examination of the effects of individual variants as well as aggregate genetic variation can clarify mechanisms ...
Adkins, Amy+16 more
core +2 more sources
Cryptic Genetic Variation in Evolutionary Developmental Genetics [PDF]
Evolutionary developmental genetics has traditionally been conducted by two groups: Molecular evolutionists who emphasize divergence between species or higher taxa, and quantitative geneticists who study variation within species. Neither approach really comes to grips with the complexities of evolutionary transitions, particularly in light of the ...
Annalise B. Paaby, Greg Gibson
openaire +4 more sources