Invasion of Europe by the western corn rootworm, Diabrotica virgifera virgifera: multiple transatlantic introductions with various reductions of genetic diversity [PDF]
, 2008 The early stages of invasion involve demographic bottlenecks that may result in lower genetic variation in introduced populations as compared to source population/s. Low genetic variability may decrease the adaptive potential of such populations in their
Arnaud-Haond +68 more
core +3 more sources
Impact of pharmacogenetics on aspirin resistance: a systematic review
Arquivos de Neuro-Psiquiatria, 2023 BackgroundâPharmacogenetics promises better control of diseases such as cardiovascular disease (CVD). Acetylsalicylic acid, aspirin, prevents the formation of an activating agent of platelet aggregation and vasoconstriction, and it is used to prevent CVD.
Gustavo Figueiredo da Silva +3 more
doaj +1 more source
Translational regulation contributes to the elevated CO2 response in two Solanum species. [PDF]
, 2020 Understanding the impact of elevated CO2 (eCO2 ) in global agriculture is important given climate change projections. Breeding climate-resilient crops depends on genetic variation within naturally varying populations.
Brady, Siobhan M +6 more
core +2 more sources
Ironing out the details: Untangling dietary iron and genetic background in diabetes [PDF]
, 2018 The search for genetic risk factors in type-II diabetes has been hindered by a failure to consider dietary variables. Dietary nutrients impact metabolic disease risk and severity and are essential to maintaining metabolic health.
Lawson, Heather A, Miranda, Mario A
core +2 more sources
Assessment of the dynamics of microparasite infections in genetically homogeneous and heterogeneous populations using a stochastic epidemic model [PDF]
, 2008 The aim of this paper was to explore the effect of genetic heterogeneity in host resistance to infection on the population-level risks and outcomes of epidemics.
Bishop, S. C. +2 more
core +1 more source
Assessment of Genetic Diversity and Conservation in South African Indigenous Goat Ecotypes: A Review
Animals, 2022 Goats were amongst the first livestock to be domesticated more than 10,000 years ago for their meat, milk, skin, and fiber. They were introduced to Southern Africa by migrating nations from Central Africa to the south.
Aletta Matshidiso Magoro +3 more
doaj +1 more source
Visualizing genetic constraints [PDF]
, 2013 Principal Components Analysis (PCA) is a common way to study the sources of variation in a high-dimensional data set. Typically, the leading principal components are used to understand the variation in the data or to reduce the dimension of the data for ...
Gaydos, Travis L. +6 more
core +3 more sources
The Genetic Basis of Mutation Rate Variation in Yeast. [PDF]
, 2018 Mutations are the root source of genetic variation and underlie the process of evolution. Although the rates at which mutations occur vary considerably between species, little is known about differences within species, or the genetic and molecular basis ...
Bloom, Joshua S +2 more
core +1 more source
The role of mutation rate variation and genetic diversity in the architecture of human disease [PDF]
, 2013 Background We have investigated the role that the mutation rate and the structure of genetic variation at a locus play in determining whether a gene is involved in disease.
A Hodgkinson +29 more
core +10 more sources
The Stabilizing Effect Of Intraspecific Genetic Variation On Population Dynamics In Novel And Ancestral Habitats [PDF]
, 2009 Recent studies show that intraspecific genetic variation in asexual species may have large effects on community and ecosystem functions, increasing their stability, productivity, and species richness.
Agashe, Deepa
core +1 more source