Results 101 to 110 of about 123,260 (289)
FEBS Open Bio, EarlyView.We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques +5 more
wiley +1 more source
A Variational Beam Model for Failure of Cellular and Truss‐Based Architected Materials
Advanced Engineering Materials, EarlyView., 2023 Herein, a versatile and efficient beam modeling framework is developed to predict the nonlinear response and failure of cellular, truss‐based, and woven architected materials. It enables the exploration of their design space and the optimization of their mechanical behavior in the nonlinear regime. A variational formulation of a beam model is presented
Konstantinos Karapiperis +3 more
wiley +1 more source
Induction of male sterility through manipulation of genetic mechanisms present in vector species of Triatominae. II. Partial restoration of male fertility [PDF]
, 1976 A Perlowagora-Szumlewicz +2 more
openalex +1 more source
FEBS Open Bio, EarlyView.Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano +16 more
wiley +1 more source
Applications and developments of gene therapy drug delivery systems for genetic diseases
Asian Journal of Pharmaceutical Sciences, 2021 Genetic diseases seriously threaten human health and have always been one of the refractory conditions facing humanity. Currently, gene therapy drugs such as siRNA, shRNA, antisense oligonucleotide, CRISPR/Cas9 system, plasmid DNA and miRNA have shown ...
Xiuhua Pan +6 more
doaj
The Evolution of Adenoviral Vectors through Genetic and Chemical Surface Modifications
Viruses, 2014 A long time has passed since the first clinical trial with adenoviral (Ad) vectors. Despite being very promising, Ad vectors soon revealed their limitations in human clinical trials.
Cristian Capasso +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley +1 more source
Asynchronous Transmission of Wireless Multicast System with Genetic Joint Antennas Selection [PDF]
IEEE WCNC 2013 workshop on Convergence of Broadcasting and
Broadband Communications. Shanghai, China: April , pp.1-5, 2014 Optimal antenna selection algorithm of multicast transmission can significantly reduce the number of antennas and can acquire lower complexity and high performance which is close to that of exhaustive search. An asynchronous multicast transmission mechanism based on genetic antenna selection is proposed.
arxiv
Fluorescently Labeled Adenovirus with pIX-EGFP for Vector Detection
Molecular Imaging, 2004 Adenoviruses are extensively studied in terms of their use as gene therapy vectors and pathogenesis. These vectors have been targeted on both transcriptional and transductional levels to achieve cell-specific gene delivery.
Long P. Le +5 more
doaj +1 more source
GENETIC MANIPULATION OF HUMAN HEMATOPOIETIC CELLS WITH RETROVIRUS VECTORS [PDF]
, 1987 Zeev Estrov +2 more
openalex +1 more source