Results 111 to 120 of about 634,337 (325)
Genetic tools for Sulfolobus spp.: vectors and first applications [PDF]
, 2018 Sulfolobus species belong to the best-studied archaeal organisms but have lacked powerful genetic methods. Recently, there has been considerable progress in the field of Sulfolobus genetics.
Berkner, Silvia, Lipps, Georg
core
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Properties and use of novel replication-competent vectors based on Semliki Forest virus
Virology Journal, 2009 Background Semliki Forest virus (SFV) has a positive strand RNA genome and infects different cells of vertebrates and invertebrates. The 5' two-thirds of the genome encodes non-structural proteins that are required for virus replication and synthesis of ...
Lulla Valeria +5 more
doaj +1 more source
Modeling the band gap of spinel nano-ferrite material using a genetic algorithm based support vector regression computational method [PDF]
, 2023 Sunday O. Olatunji, Taoreed O. Owolabi
openalex +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Genetic Targeting of Adenoviral Vectors
Molecular Therapy, 2000 Krasnykh, V N +2 more
openaire +4 more sources
Fluorescently Labeled Adenovirus with pIX-EGFP for Vector Detection
Molecular Imaging, 2004 Adenoviruses are extensively studied in terms of their use as gene therapy vectors and pathogenesis. These vectors have been targeted on both transcriptional and transductional levels to achieve cell-specific gene delivery.
Long P. Le +5 more
doaj +1 more source
Metabolic Engineering Communications, 2016 Clostridium thermocellum is a leading candidate for the consolidated bioprocessing of lignocellulosic biomass for the production of fuels and chemicals.
Joseph Groom +5 more
doaj +1 more source