Results 111 to 120 of about 123,260 (289)
FEBS Open Bio, EarlyView.IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He +5 more
wiley +1 more source
Highly Efficient Human Action Recognition with Quantum Genetic Algorithm Optimized Support Vector Machine [PDF]
arXiv, 2017 In this paper we propose the use of quantum genetic algorithm to optimize the support vector machine (SVM) for human action recognition. The Microsoft Kinect sensor can be used for skeleton tracking, which provides the joints' position data. However, how to extract the motion features for representing the dynamics of a human skeleton is still a ...
arxiv
Integrating Retroviral Cassette Extends Gene Delivery of HSV-1 Expression Vectors to Dividing Cells
BioTechniques, 2001 Retroviral vectors have long been used in a wide variety of gene transfer applications but have certain drawbacks, such as small cargo size, limited tropism, and low titers.
Pablo de Felipe +3 more
doaj +1 more source
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source
A General Framework of Brain Region Detection And Genetic Variants Selection in Imaging Genetics [PDF]
arXivImaging genetics is a growing field that employs structural or functional neuroimaging techniques to study individuals with genetic risk variants potentially linked to specific illnesses. This area presents considerable challenges to statisticians due to the heterogeneous information and different data forms it involves.
arxiv
A generalized financial time series forecasting model based on automatic feature engineering using genetic algorithms and support vector machine [PDF]
arXiv, 2018 We propose the genetic algorithm for time window optimization, which is an embedded genetic algorithm (GA), to optimize the time window (TW) of the attributes using feature selection and support vector machine. This GA is evolved using the results of a trading simulation, and it determines the best TW for each technical indicator.
arxiv
Molecular phylogeny of the Anopheles gambiae complex suggests genetic introgression between principal malaria vectors. [PDF]
, 1994 Nora J. Besansky +5 more
openalex +1 more source
Tsetse flies: Genetics, evolution, and role as vectors [PDF]
Infection, Genetics and Evolution, 2009 Tsetse flies (Diptera: Glossinidae) are an ancient taxon of one genus, Glossina, and limited species diversity. All are exclusively haematophagous and confined to sub-Saharan Africa. The Glossina are the principal vectors of African trypanosomes Trypanosoma sp. (Kinetoplastida: Trypanosomatidae) and as such, are of great medical and economic importance.
openaire +3 more sources
FEBS Open Bio, EarlyView.This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma +3 more
wiley +1 more source
Chinese Journal of Lung Cancer, 2008 Background and objective The drug resistance to chemotherapeutics is one of the important causes of low survival rate of lung cancer patients.
Xuejun LI, Heping YANG, Xiangdong ZHOU
doaj