Dendritic Cells Genetically Modified with an Adenovirus Vector Encoding the cDNA for a Model Antigen Induce Protective and Therapeutic Antitumor Immunity [PDF]
Wenru Song+7 more
openalex +1 more source
The evolution and genetics of vector competence in mosquito disease vectors
Vector competence is a complex characteristic which governs an insect's ability to acquire, support the development and transmit a parasite from one host to another. It influences variation in disease transmission among mosquito populations, hence affecting disease epidemiology.
openaire +2 more sources
Mapping Hsp104 interactions using cross‐linking mass spectrometry
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal+3 more
wiley +1 more source
An Efficient Sufficient Dimension Reduction Method for Identifying Genetic Variants of Clinical Significance [PDF]
Fast and cheaper next generation sequencing technologies will generate unprecedentedly massive and highly-dimensional genomic and epigenomic variation data. In the near future, a routine part of medical record will include the sequenced genomes. A fundamental question is how to efficiently extract genomic and epigenomic variants of clinical utility ...
arxiv
Characterization of CD8+ cytotoxic T-lymphocyte responses after genetic immunization with retrovirus vectors expressing different forms of the hepatitis B virus core and e antigens [PDF]
Kay Townsend+10 more
openalex +1 more source
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao+4 more
wiley +1 more source
Rickettsia Species: Genetic Variability, Vectors, and Rickettsiosis—A Review
Rickettsiae are an interesting group of bacteria comprising a large number of obligate intracellular species. The circulation of these bacteria in the environment depends on the presence of vectors (blood-sucking invertebrates) and their hosts.
Anna Rymaszewska, Mariusz Piotrowski
doaj +1 more source
Genetic variation in arthropod vectors of disease-causing organisms: obstacles and opportunities [PDF]
R. H. Gooding
openalex +1 more source
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang+5 more
wiley +1 more source
Depolarization induced by subwavelength metal hole arrays [PDF]
We present a symmetry-based theory of the depolarization induced by subwavelength metal hole arrays. We derive the Mueller matrices of hole arrays with various symmetries (in particular square and hexagonal) when illuminated by a finite-diameter (e.g. gaussian) beam.
arxiv