Results 131 to 140 of about 123,260 (289)
Genetic variability and differentiation between populations of Rhodnius prolixus and R. pallescens, vectors of Chagas' Disease in Colombia [PDF]
Germán M. López‐Iborra, Jaime Moreno
openalex +1 more source
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei+6 more
wiley +1 more source
Outlier Detection using Improved Genetic K-means [PDF]
The outlier detection problem in some cases is similar to the classification problem. For example, the main concern of clustering-based outlier detection algorithms is to find clusters and outliers, which are often regarded as noise that should be removed in order to make more reliable clustering.
arxiv
Control of Vector‐Borne Disease by Genetic Manipulation of Insect Populations: Technological Requirements and Research Priorities [PDF]
Melinda M. Pettigrew, Scott L. O’Neill
openalex +1 more source
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel+4 more
wiley +1 more source
Faster Genetic Programming GPquick via multicore and Advanced Vector Extensions [PDF]
We evolve floating point Sextic polynomial populations of genetic programming binary trees for up to a million generations. Programs with almost four hundred million instructions are created by crossover. To support unbounded Long-Term Evolution Experiment LTEE GP we use both SIMD parallel AVX 512 bit instructions and 48 threads to yield performance of
arxiv
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel+13 more
wiley +1 more source
In vivo correction of genetic defects of monocyte/ macrophages using attenuated Salmonella as oral vectors for targeted gene delivery [PDF]
Paola Paglia+4 more
openalex +1 more source
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu+6 more
wiley +1 more source