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Genetic technologies for disease vectors
Current Opinion in Insect Science, 2015The first genetic technologies for insect vectors of disease were introduced 20 years ago. As of today there are 12 classes of genetic technologies used as functional genomic tools for insect vectors of important diseases. Although the applications of genetic technologies in insect disease vectors have been conducted primarily in mosquitoes, other ...
Frank, Criscione +2 more
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Molecular Genetic Manipulation of Mosquito Vectors
Annual Review of Entomology, 1995Despite their central role in disease transmission, relatively little is known of the molecular biology of arthropod vectors. Modern molecular approaches will undoubtedly provide considerable information about gene regulation and expression in vectors and consequently a much better understanding of the biology and molecular biology of vectors.
J, Carlson, K, Olson, S, Higgs, B, Beaty
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1995
Since the pioneering studies of Edward Jenner on using live virus vaccines during the early 1800s (Baxby 1981), a considerable amount of information has been obtained on the biology and replication of poxviruses. Vaccinia virus, the agent used to vaccinate humans against smallpox and eradicate this disease, has been widely studied in the laboratory due
William I. Cox +2 more
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Since the pioneering studies of Edward Jenner on using live virus vaccines during the early 1800s (Baxby 1981), a considerable amount of information has been obtained on the biology and replication of poxviruses. Vaccinia virus, the agent used to vaccinate humans against smallpox and eradicate this disease, has been widely studied in the laboratory due
William I. Cox +2 more
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Adenoassociated virus vectors for genetic immunization
Immunologic Research, 2002Genetic immunization has initiated a new era of vaccine research, which provides a stable and long-lived source of the protein antigen. Such a vaccine is a simple, robust, and effective means of eliciting both antibody- and cell-mediated immune responses compared with protein or peptide vaccines.
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Herpesviruses as Genetic Vectors
1995The members of the Herpesviridae family are large, DNA-containing, enveloped viruses. Nearly 100 herpesviruses infect a broad spectrum of the animal kingdom (Roizman 1990). So far, seven different types of human herpesviruses have been described (Table 5.1).
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Genetic Modification of Chondrocytes Using Viral Vectors
2010The use of isolated cells to construct engineered tissues provides the opportunity to genetically modify those cells prior to the formation of tissue. This should make it possible to create transgenic human model tissues that can be used to determine gene function as well as to identify or validate potential therapeutic targets.
Teresa, Coughlan +3 more
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Efficient vector quantization using genetic algorithm
Neural Computing and Applications, 2005This paper proposes a new codebook generation algorithm for image data compression using a combined scheme of principal component analysis (PCA) and genetic algorithm (GA). The combined scheme makes full use of the near global optimal searching ability of GA and the computation complexity reduction of PCA to compute the codebook.
Hongwei Sun +5 more
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HSV-1 Amplicon Vectors as Genetic Vaccines
2019HSV-1 amplicon vectors have been used as platforms for the generation of genetic vaccines against both DNA and RNA viruses. Mice vaccinated with such vectors encoding structural proteins from both foot-and-mouth disease virus and rotavirus were partially protected from challenge with wild-type virus (D'Antuono et al., Vaccine 28:7363-7372, 2010 ...
Anita F, Meier, Andrea S, Laimbacher
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Genetic fuzzy entropy‐constrained vector quantization
Journal of the Chinese Institute of Engineers, 2001Abstract A novel variable‐rate vector quantizer (VQ) design algorithm using both genetic and fuzzy clustering techniques is presented. The algorithm, termed genetic fuzzy entropy‐constrained VQ (GFECVQ) design algorithm, has a superior rate‐distortion performance than that of the existing variable‐rate VQ design algorithms. The algorithm utilizes fuzzy
Wen‐Jyi Hwang +2 more
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