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HSV-1 Amplicon Vectors as Genetic Vaccines
2014HSV-1 amplicon vectors have been used as platforms for the generation of genetic vaccines against both DNA and RNA viruses. Mice vaccinated with such vectors encoding structural proteins from both foot-and-mouth disease virus and rotavirus were partially protected from challenge with wild-type virus (D'Antuono et al.
Laimbacher, A S, Fraefel, C
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Genetics of a Molluscan Vector of Schistosomiasis
Nature, 1970A complex of several genetic factors determines the susceptibility of juvenile Biomphalaria glabratus to infection by Schistosoma mansoni. A simple dominant factor can cause juvenile susceptible snails to become refractory to the parasite at maturity. Stocks of such adults may prove to be of use in genetic control of S. mansoni in endemic areas.
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Vector quantizer design using genetic algorithms
Proceedings of Data Compression Conference - DCC '96, 2002The design of vector quantizers (VQs) that yield minimal distortion is one of the most challenging problems in source coding. The problem of VQ design is to find a codebook that gives the least overall distortion (or equivalently, the largest signal-to-noise ratio (SNR)) for a given set of input vectors.
null Sunghyun Choi, null Wee-Keong Ng
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Genetic make-up of arthropod vectors
Revue Scientifique et Technique de l'OIE, 2015A better understanding of the molecular aspects of arthropod vector biology and the processes that determine pathogen transmission can lead to the development of novel or improved control methods for vectors and vector-borne diseases. The 'omics' era provides unprecedented opportunities to explore these aspects of vectors and the diseases which they ...
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Compact Genetic Algorithms using belief vectors
Applied Soft Computing, 2011Abstract: Instead of the genetic operators such as crossover and mutation, compact Genetic Algorithms (cGAs) use a probability vector (PV) for the current population to reproduce offsprings of the next generation. Therefore, the original cGA can be easily implemented with no parameter tuning of the genetic operators and with reducing memory ...
Lee, JY Lee, Joon-Yong +2 more
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Vector Genetics in Malaria Control
2006Anopheles culicifacies is the major vector of rural malaria in the plains of India. Cytogenetic analysis of polytene chromosomes revealed that A. culicifacies is a complex of five sibling species designated as A, B, C, D, and E. Each sibling species has its own distribution pattern which is influenced by the environment. Sibling species differ in their
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Genetically Engineering Adenoviral Vectors for Gene Therapy
2013Adenoviral (Ad) vectors are commonly used for various gene therapy applications. Significant advances in the genetic engineering of Ad vectors in recent years has highlighted their potential for the treatment of metastatic disease. There are several methods to genetically modify the Ad genome to incorporate retargeting peptides which will redirect the ...
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FPGA implementation of genetic vector quantizers
Neurocomputing, 2010This paper presents a novel hardware architecture for genetic vector quantizer (VQ) design. It is based on steady-state genetic algorithm (GA) and adopts shift registers for accelerating mutation and crossover operations while reducing area cost. It also uses a pipeline for fitness evaluation.
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Synthetic Vectors for Genetic Drug Delivery
2006Gene therapy is a new approach in the treatment of numerous diseases caused by damage to or lack of certain genes. Its application seems to be very effective, especially in the case of cancer diseases, where genetic drugs can be designed to selectively eliminate damaged cells. Due to the chemical properties of nucleic acids, their introduction into the
Paulina Wyrozumska +3 more
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