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Genetically Engineering Adenoviral Vectors for Gene Therapy
2013Adenoviral (Ad) vectors are commonly used for various gene therapy applications. Significant advances in the genetic engineering of Ad vectors in recent years has highlighted their potential for the treatment of metastatic disease. There are several methods to genetically modify the Ad genome to incorporate retargeting peptides which will redirect the ...
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FPGA implementation of genetic vector quantizers
Neurocomputing, 2010This paper presents a novel hardware architecture for genetic vector quantizer (VQ) design. It is based on steady-state genetic algorithm (GA) and adopts shift registers for accelerating mutation and crossover operations while reducing area cost. It also uses a pipeline for fitness evaluation.
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Synthetic Vectors for Genetic Drug Delivery
2006Gene therapy is a new approach in the treatment of numerous diseases caused by damage to or lack of certain genes. Its application seems to be very effective, especially in the case of cancer diseases, where genetic drugs can be designed to selectively eliminate damaged cells. Due to the chemical properties of nucleic acids, their introduction into the
Paulina Wyrozumska +3 more
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Delivery of Genetic Information: Viral Vector and Nonviral Vector Gene Therapies
International Ophthalmology Clinics, 2021Michael, Gemayel +3 more
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Cytogenetics and Genetics of Vectors
The American Journal of Tropical Medicine and Hygiene, 1983openaire +1 more source