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1995
Since the pioneering studies of Edward Jenner on using live virus vaccines during the early 1800s (Baxby 1981), a considerable amount of information has been obtained on the biology and replication of poxviruses. Vaccinia virus, the agent used to vaccinate humans against smallpox and eradicate this disease, has been widely studied in the laboratory due
William I. Cox +2 more
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Since the pioneering studies of Edward Jenner on using live virus vaccines during the early 1800s (Baxby 1981), a considerable amount of information has been obtained on the biology and replication of poxviruses. Vaccinia virus, the agent used to vaccinate humans against smallpox and eradicate this disease, has been widely studied in the laboratory due
William I. Cox +2 more
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Herpesviruses as Genetic Vectors
1995The members of the Herpesviridae family are large, DNA-containing, enveloped viruses. Nearly 100 herpesviruses infect a broad spectrum of the animal kingdom (Roizman 1990). So far, seven different types of human herpesviruses have been described (Table 5.1).
J. Vos
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Genetic technologies for disease vectors
Current Opinion in Insect Science, 2015The first genetic technologies for insect vectors of disease were introduced 20 years ago. As of today there are 12 classes of genetic technologies used as functional genomic tools for insect vectors of important diseases. Although the applications of genetic technologies in insect disease vectors have been conducted primarily in mosquitoes, other ...
Frank, Criscione +2 more
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Exosome-mediated delivery of gene vectors for gene therapy.
Nanoscale, 2020Gene vectors are nucleic acids that carry genetic materials or gene editing devices into cells to exert the sustained production of therapeutic proteins or to correct erroneous genes of the cells.
Li Duan +7 more
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Genetic and Physical Map of the pLAFR1 Vector
DNA Sequence, 2004This paper presents the complete sequencing and annotation of the pLAFR1 vector. pLAFR is a tetracycline-resistant "cosmid" cloning vector, which is derived from the 20 kb plasmid pRK290, a RK2-derivative. Due to its broad host range, the pLAFR1 vector has been widely used in the genetic analysis of a broad number of gram-negative bacterial species ...
Els, Vanbleu +2 more
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Genetics of a Molluscan Vector of Schistosomiasis
Nature, 1970A complex of several genetic factors determines the susceptibility of juvenile Biomphalaria glabratus to infection by Schistosoma mansoni. A simple dominant factor can cause juvenile susceptible snails to become refractory to the parasite at maturity. Stocks of such adults may prove to be of use in genetic control of S. mansoni in endemic areas.
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Molecular Genetic Manipulation of Mosquito Vectors
Annual Review of Entomology, 1995Despite their central role in disease transmission, relatively little is known of the molecular biology of arthropod vectors. Modern molecular approaches will undoubtedly provide considerable information about gene regulation and expression in vectors and consequently a much better understanding of the biology and molecular biology of vectors.
J, Carlson, K, Olson, S, Higgs, B, Beaty
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Viral Vectors for Gene Transfer
Current Protocols in Mouse Biology, 2018Viral vectors are a promising tool for effective delivery of genetic material into cells. They take advantage of the natural ability of a virus to deliver a genetic payload into cells while being genetically modified such that their ability to replicate ...
Yong Hong Chen +2 more
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