Results 331 to 340 of about 4,784,986 (369)

Adenoassociated virus vectors for genetic immunization

Immunologic Research, 2002
Genetic immunization has initiated a new era of vaccine research, which provides a stable and long-lived source of the protein antigen. Such a vaccine is a simple, robust, and effective means of eliciting both antibody- and cell-mediated immune responses compared with protein or peptide vaccines.
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Genetic manipulation of insect vectors as a strategy for the control of vector-borne disease

Annals of Tropical Medicine & Parasitology, 1994
A variety of very effective methods have been employed for suppressing insect vector populations, including the application of biological control agents and the elimination of breeding sites, with a continuing and heavy reliance on the use of chemical insecticides.
J M, Crampton, A, Warren, G J, Lycett, M A, Hughes, I P, Comley, P, Eggleston   +5 more
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Plasmid RP4 as a vector replicon in genetic engineering

Nature, 1975
THERE is now considerable interest in the construction of plasmids containing DNA fragments from a variety of bacterial genera, for purposes of studying the expression of the genetic potentialities of the incorporated bacterial DNA in different bacterial hosts.
A E, Jacob, N J, Grinter
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Genetic manipulation of endothelial cells by viral vectors

Thrombosis and Haemostasis, 2009
SummaryThe need for uncovering molecular mechanisms in endothelial cell biology has tremendously increased in the last decades as it became more and more clear that the endothelium is an important target in nearly all diseases and treatments (drug delivery) and plays a central role in regeneration processes.
Dirk, Lindemann, Hans, Schnittler
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Genetic modification of lymphocytes by retrovirus-based vectors

Current Opinion in Immunology, 2012
The genetic modification of lymphocytes is an important topic in the emerging field of gene therapy. Many clinical trials targeting immunodeficiency syndromes or cancer have shown therapeutic benefit; further applications address inflammatory and infectious disorders.
Julia D, Suerth, Axel, Schambach, Christopher, Baum   +2 more
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Genetic Modification of Chondrocytes Using Viral Vectors

2010
The use of isolated cells to construct engineered tissues provides the opportunity to genetically modify those cells prior to the formation of tissue. This should make it possible to create transgenic human model tissues that can be used to determine gene function as well as to identify or validate potential therapeutic targets.
Teresa, Coughlan, Aileen, Crawford, Paul, Hatton, Michael, Barker   +3 more
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HSV-1 Amplicon Vectors as Genetic Vaccines

2019
HSV-1 amplicon vectors have been used as platforms for the generation of genetic vaccines against both DNA and RNA viruses. Mice vaccinated with such vectors encoding structural proteins from both foot-and-mouth disease virus and rotavirus were partially protected from challenge with wild-type virus (D'Antuono et al., Vaccine 28:7363-7372, 2010 ...
Anita F, Meier, Andrea S, Laimbacher
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Entrapment Vectors: A New Tool for Mammalian Genetics

Nature Biotechnology, 1990
The use of mouse embryonic stem (ES) cells has facilitated the creation of mouse strains carrying desired genetic alterations. Recently, "entrapment" vectors have been developed to identify and mutate genes active during embryogenesis. These vectors in combination with ES cells may provide an efficient screening strategy to find genes that control ...
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Vector Genetics in Malaria Control

2006
Anopheles culicifacies is the major vector of rural malaria in the plains of India. Cytogenetic analysis of polytene chromosomes revealed that A. culicifacies is a complex of five sibling species designated as A, B, C, D, and E. Each sibling species has its own distribution pattern which is influenced by the environment. Sibling species differ in their
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HSV-1 Amplicon Vectors as Genetic Vaccines

2014
HSV-1 amplicon vectors have been used as platforms for the generation of genetic vaccines against both DNA and RNA viruses. Mice vaccinated with such vectors encoding structural proteins from both foot-and-mouth disease virus and rotavirus were partially protected from challenge with wild-type virus (D'Antuono et al.
Laimbacher, A S, Fraefel, C
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