Results 41 to 50 of about 143,498 (285)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

UC researchers evaluating genetically engineered alfalfa

open access: yesCalifornia Agriculture, 2004
California Agriculture - All ...
J Warnert
doaj   +3 more sources

Genetically engineered foods: corn [PDF]

open access: yes, 2002
2 pages.Fact sheet about genetically-engineered ...
Genetically Engineered Organisms Public Issues Education Project
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Sexual dimorphism in the effects of maternal adipose tissue growth hormone receptor deficiency on offspring metabolic health

open access: yesBiology of Sex Differences
Background The global incidence of obesity continues to rise, which increases the prevalence of metabolic diseases. We previously demonstrated the beneficial effect of adipose-specific growth hormone receptor (Ghr) knockout (KO) on metabolic parameters ...
Liyuan Ran   +5 more
doaj   +1 more source

Genetically engineered foods: Tomatoes [PDF]

open access: yes, 2002
2 pages.Fact sheet about genetically-engineered ...
Genetically Engineered Organisms Public Issues Education Project
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Genetically engineered foods: U.S. safety regulation of genetically engineered crops [PDF]

open access: yes, 2002
4 pages.Fact sheet about U.S.
Genetically Engineered Organisms Public Issues Education Project
core  

Genetic engineering for the environment: Ethical implications of the biotechnology revolution [PDF]

open access: yes, 1995
This is a PDF version of an article published in Heythrop Journal© 1995. The definitive version is available at www.blackwell-synergy.com.This article discusses the environmental consequences of genetic engineering for agricultural purposes within a ...
Deane-Drummond, Celia
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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