Results 121 to 130 of about 3,096,858 (303)

Attitudes towards genetically modified animals in food production

open access: yes, 2014
Purpose – Food products developed using genetically modified (GM) animals may soon be introduced in Europe and beyond. Their successful commercialisation depends on consumer acceptance, and so it is timely to review the existing literature in this ...
Coles, David   +10 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

ISSUES IN DEVELOPMENT AND ADOPTION OF GENETICALLY MODIFIED (GM) WHEATS [PDF]

open access: yes
Development of genetically modified (GM) wheat varieties is proceeding; however, several critical issues remain the focus of contention. This project summarizes the current state of knowledge on some of these critical issues for commercialization of GM ...
Janzen, Edward L.   +3 more
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

The Price and Trade Effects of Strict Information Requirements for Genetically Modified Commodities under the Cartagena Protocol on Biosafety [PDF]

open access: yes
The Price and Trade Effects of Strict Information Requirements for Genetically Modified Commodities under the Cartagena Protocol on ...
Antoine BOUET   +2 more
core  

Cancer vaccines: uses of HLA transgenic mice compared to genetically modified mice [PDF]

open access: yes, 2008
Many tumor antigens have been identified that can be targeted by the immune system. Animal models that have been genetically modified to express human HLA molecules instead of their own MHC antigens have shown to be valuable in the discovery of peptides ...
McArdle, SE
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

CONSUMER ACCEPTANCE OF GENETICALLY MODIFIED FOODS: A PROFILE OF AMERICAN CONSUMERS [PDF]

open access: yes
A telephone survey was conducted on genetically modified foods in the U.S. Consumers' attitudes are studied using a multiple correspondence analysis, and typology constructed through the use of a cluster analysis.
Ganiere, Pierre, Chern, Wen S.
core  

Reviving the Dire Wolf? A Case Study in Welfare Ethics, Legal Gaps, and Ontological Ambiguity

open access: yesAnimals
The recent birth of genetically modified canids phenotypically resembling the extinct dire wolf (Aenocyon dirus) was hailed as a landmark in synthetic biology.
Alexandre Azevedo   +1 more
doaj   +1 more source

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