Results 121 to 130 of about 313,603 (373)

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic   +6 more
wiley   +1 more source

Post Market Environmental Monitoring of Genetically Modified Herbicide Tolerant Crops (Working group report from the 4th International Workshop on PMEM of Genetically Modified Plants, Quedlinburg, Germany 2010)

open access: yesJournal für Kulturpflanzen, 2011
According to European Union (EU) legislation, genetically modified (GM) crops released for commercial cultivation have to be monitored. Here we summarise the discussion of a working group that convened during the 4th International Workshop on Post Market
Olivier Sanvido   +3 more
doaj   +1 more source

Inventory of observed unexpected environmental effects of genetically modified crops [PDF]

open access: yes
In general, it can be concluded that very few clearly unexpected effects were observed during the large scale post-release growing of herbicide-tolerant crops and Bt crops.
Brink, L., van den   +6 more
core   +1 more source

Environmental risk assessment of genetically modified plants - concepts and controversies [PDF]

open access: yes, 2011
Background and purpose: In Europe, the EU Directive 2001/18/EC lays out the main provisions of environmental risk assessment (ERA) of genetically modified (GM) organisms that are interpreted very differently by different stakeholders. The purpose of this
A Hilbeck   +57 more
core   +1 more source

Georgian Farmers’ Attitudes Towards Genetically Modified Crops

open access: yes, 2017
Although, genetically engineered products (GM) have to be a broadly debated topic in different countries, there has been much less attention devoted to farmers’ attitudes towards GM crops.
Nugzar Todua, T. Gogitidze
semanticscholar   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

A chromosome-level genome assembly of Mylabris sibirica Fischer von Waldheim, 1823 (Coleoptera, Meloidae)

open access: yesScientific Data
Mylabris sibirica is a hypermetamorphic insect that primarily feeds on oilseed rape during the adult stage. However, the limited availability of genomic resources hinders our understanding of the gene function, medical use, and ecological adaptation in M.
Chenhui Shen   +11 more
doaj   +1 more source

Legislation governing genetically modified and genome‐edited crops in Europe: the need for change

open access: yesThe Journal of the Science of Food and Agriculture, 2018
The European Commission's assessment and approval process for genetically modified (GM) crops has resulted in only two GM crop varieties being licensed for cultivation in the European Union, one of which has been withdrawn.
Nigel G Halford
semanticscholar   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

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