57Fe enrichment in mice for \b{eta}-thalassaemia studies via Mossbauer spectroscopy of blood samples [PDF]
arXiv, 2019 In this work, wild-type and heterozygous \b{eta}-thalassaemic mice were enriched with 57Fe through gastrointestinal absorption to characterize in more details the iron complexes appeared in the measured Mossbauer spectra. The 57Fe enrichment method was validated and Mossbauer spectra were obtained at 80K from blood samples from wild-type and \b{eta ...
arxiv
316. Therapeutic Potential of Genetically Modified Neural Stem Cells (NSCs) in a Mouse Model of Globoid Cells Leukodystrophy (GLD) [PDF]
, 2010 openalex +1 more source
Liquid-phase imaging of bone development and calcification by atmospheric scanning electron microscopy (ASEM): Application to immuno-labeling and rapid tissue observation of genetically modified mouse [PDF]
, 2021 Eiko Sakai +4 more
openalex +1 more source
The study of genetically modified soybeans mutagenic effects in drosophila and mouse
Ecological genetics, 2015 The use of genetically modified soybeans (GM) as a food substrate during Drosophila reproduction, as well as the addition of GM-soybeans in the standard mice meal showed no mutagenic effect on criteria recessive sex-linked lethal mutations (RSPLM) and dominant mutations (DM) in Drosophila and abnormal sperm in mice.
Larisa V Barabanova +1 more
openaire +3 more sources
Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification
FEBS Open Bio, EarlyView.Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski +13 more
wiley +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
FEBS Open Bio, EarlyView.Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa +13 more
wiley +1 more source
Exosomes derived from mesenchymal stem cells improved core symptoms of genetically modified mouse model of autism Shank3B. [PDF]
Mol Autism, 2020 Perets N +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo +4 more
wiley +1 more source