Results 211 to 220 of about 2,416,740 (342)

Environmental Release of Genetically Intervened Microorganisms: Towards a New Narrative. [PDF]

Microb Biotechnol
de Lorenzo V.
europepmc   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

This I Believe: Agricultural Science and Genetics

Frontiers in Genetics, 2012
M S Swaminathan
doaj   +1 more source

Reading Conflicting Socio-Scientific Issue Texts: Visual and Post-Reading Myside Bias. [PDF]

J Eye Mov Res
Ban S, Mahmud SND, Osman K.
europepmc   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Considerations for Postrelease Environmental Safety Monitoring of Gene Drive-Modified Mosquitoes as a Tool for Malaria Control in Sub-Saharan Africa. [PDF]

Am J Trop Med Hyg
Abram PK, Bouyer J, Dass B, Ogoyi D, Okumu F, Overcash J, James SL.   +6 more
europepmc   +1 more source

A Generative Neuro‐Symbolic AI for Protein Sequence Design

Advanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne, Delphine Dessaux, Samuel Buchet, Lucie Barthe, Liza Ammar‐Khodja, Bessam Azizi, Valentin Durante, Gianluca Cioci, Simon de Givry, Alain Roussel, Luis F. Garcia‐Alles, Thomas Schiex, Sophie Barbe   +12 more
wiley   +1 more source

Editorial: Role of nutrition in skeletal muscle atrophy and sarcopenia

Frontiers in Nutrition
Tao Tong, Tao Tong, Tao Tong, Helong Quan, Chang Keun Kim, Weicai Zeng   +5 more
doaj   +1 more source

Special Issue "Zebrafish: A Model Organism for Human Health and Disease: 2nd Edition". [PDF]

Int J Mol Sci
Kanungo J.
europepmc   +1 more source