Results 71 to 80 of about 1,455,121 (302)

Behavioral genetics in criminal cases: past, present, and future

, 2006
Researchers studying human behavioral genetics have made significant scientific progress in enhancing our understanding of the relative contributions of genetics and the environment in observed variations in human behavior. Quickly outpacing the advances
Farahany, Nita, Bernet, William
core  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Genetic and Environmental Predictors of Adolescent PTSD Symptom Trajectories Following a Natural Disaster

Brain Sciences, 2019
Genes, environmental factors, and their interplay affect posttrauma symptoms. Although environmental predictors of the longitudinal course of posttraumatic stress disorder (PTSD) symptoms are documented, there remains a need to incorporate genetic risk ...
Christina M. Sheerin, Laurel V. Kovalchick, Cassie Overstreet, Lance M. Rappaport, Vernell Williamson, Vladimir Vladimirov, Kenneth J. Ruggiero, Ananda B. Amstadter   +7 more
doaj   +1 more source

Genes Found and Lost: Misperceptions of Behavioral Genetics

, 2000
review of BEHAVIORAL GENETICS: THE CLASH OF CULTURE AND BIOLOGY, by Ronald A. Carson and Mark A.
Alper, Joseph S., Beckwith, Jonathan R.
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Behavioral Genetics

, 2020
Excerpt Behavioral genetics is a field of scientific research that aims to understand how much genetic and environmental factors contribute to variability in behavior.
Strong, Ashley R, Lashley, Lisa K, Golden, Charles J   +2 more
core   +1 more source

Examining the genetic links between clusters of immune-mediated diseases and psychiatric disorders

Translational Psychiatry
Extant phenotypic and genetic literature has established consistent relationships between autoimmune, autoinflammatory, and psychiatric disorders. However, a comprehensive model investigating the association between a broad range of psychiatric disorders
Sophie Breunig, Younga Heather Lee, Elizabeth W. Karlson, Arjun Krishnan, Jeremy M. Lawrence, Lukas S. Schaffer, Andrew D. Grotzinger   +6 more
doaj   +1 more source

Genetic influences on the human oral microbiome

BMC Genomics, 2017
Background The human oral microbiome is formed early in development. Its composition is influenced by environmental factors including diet, substance use, oral health, and overall health and disease.
Brittany A. Demmitt, Robin P. Corley, Brooke M. Huibregtse, Matthew C. Keller, John K. Hewitt, Matthew B. McQueen, Rob Knight, Ivy McDermott, Kenneth S. Krauter   +8 more
doaj   +1 more source

The origins of behavioral genetics [PDF]

Current Biology, 2008
The passing of Seymour Benzer has inspired various retrospectives on his scientific career, and much attention has been paid to his inauguration of single-gene mutant studies of behavior in the fruitfly Drosophila melanogaster. Studies of genes and behavior actually go back to the beginnings of genetics.
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source