Results 121 to 130 of about 753,352 (304)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Code of Ethical Principles for Genetics Professionals

, 1996
see also: Code of Ethical Principles for Genetics Professionals: An Explication in American Journal of Medical Genetics 1996 October 28; 65(3): 179 ...
Henderson, Merrill, Roper Willson, Nancy, Lebel, Robert, Fisher, Nancy, Pelias, Mary Z., Fox, Lynda, McGrath, Geraldine, Baumiller, Robert C., Cunningham, George, Comley, Sarah, Porter, Ian   +10 more
core  

Using OMIM (On-line Mendelian Inheritance in Man) as an expert system in medical genetics

, 1991
Expert systems have been used in Medicine for many years, but they are usually highly sophisticated and not well integrated into day-to-day practice.
Schorderet, D. F.
core   +1 more source

VIEWS OF GROUP OF PHISICIANS, NURCES AND MIDWIVES ON ETHICAL PRINCIPLES IN MEDICAL GENETICS, IN TEHRAN

Iranian Journal of Public Health, 1999
In 1998 international guidelines on principles of ethics in medical genetics and genetic services was edited and provided by the World Health Organization.
D.D. Farhud, N. Nickzat, M. Mahmoodi   +2 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Current approach to genetic testing and genetic evaluation referrals for adults with congenital heart disease

Background: Congenital heart disease (CHD) is the most common congenital anomaly. Up to 33% have an identifiable genetic etiology. Improved medical and surgical management of CHD has translated into longer life expectancy and a rapidly growing population
Opotowsky, Alexander R., Miller, Erin M., Oehlman, Laura B., He, Hua, Barnett, Cara L., Weaver, Kathryn N., Brown, Nicole M., Shikany, Amy R.   +7 more
core   +1 more source

History of medical genetics

, 2013
This article is a revision of the previous edition article by Victor A McKusick, volume 1, pp 3–32, © 2007, Elsevier Ltd. During the past 60 years, since Medical Genetics first became a defined field of genetics, and a medical specialty in its own ...
Harper, Peter Stanley, Peter S. Harper, McKusick, Victor A., Victor A. McKusick   +3 more
core   +1 more source

Basic concepts of medical genetics formal genetics, Part 3

Egyptian Journal of Medical Human Genetics, 2014
Mohammad Saad Zaghloul Salem
doaj   +1 more source

Associations between genetics, medical status, physical exercise and psychological well-being in adults with cystic fibrosis. [PDF]

BMJ Open Respir Res, 2016
Backström-Eriksson L, Bergsten-Brucefors A, Hjelte L, Melin B, Sorjonen K.   +4 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source