Results 51 to 60 of about 5,449,771 (353)
Genetics in medical practice [PDF]
Genetics in Medicine, 2002 Medical genetics has been formally recognized as a medical specialty in the United States only within the past decade. Initially, medical genetics was concerned with relatively rare single gene or chromosomal disorders, but with the sequencing of the human genome, genetics has become the driving force in medical research and is now poised for ...
openaire +2 more sources
Health Care Challenges of Hereditary Common Hematological Disorders in Odisha, India [PDF]
, 2012 Medical Genetics over the past few decades have emerged as an important and powerful medical specialty with increasing appreciation of its role and function in the biomedical sciences.
Balgir, RS
core +1 more source
Medical genetics and epigenetics of telomerase [PDF]
, 2011 Telomerase is a specialized reverse transcriptase that extends and maintains the terminal ends of chromosomes, or telomeres. Since its discovery in 1985 by Nobel Laureates Elizabeth Blackburn and Carol Greider, thousands of articles have emerged ...
Fox, Melanie J. +4 more
core +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
F1000Research, 2014 Positive identification of the nature of biological material present on evidentiary items can be crucial for understanding the circumstances surrounding a crime.
Erin K. Hanson, Jack Ballantyne
doaj +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
F1000Research, 2015 The study of primary cilia is of broad interest both in terms of disease pathogenesis and the fundamental biological role of these structures. Murine models of ciliopathies provide valuable tools for the study of these diseases.
Simon Ramsbottom +2 more
doaj +1 more source
Comparison of Fluorescein Isothiocyanate-Conjugated and Texas-Red-Conjugated Nucleotides for Direct Labeling in Comparative Genomic Hybridization [PDF]
, 1998 Fil: Larramendy, Marcelo Luis. Cátedra de Citología. Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; ArgentinaFil: Elrifai, Wa`el. Department of Medical Genetics. Haartman Institute. University of Helsinki. Helsinki; FinlandFil:
Elrifai, Wa`el +2 more
core
BEGIN Partnership: Using Problem-Based Learning to Teach Genetics & Bioethics [PDF]
, 2008 A science education center at a university medical school had grant funding to develop a genetics curriculum unit, but needed a dissemination plan.
Chen, Shaw-Ree +4 more
core +2 more sources
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source