Results 81 to 90 of about 675,403 (292)
Public Health Genomics, 2004 Peru has a growing population characterized by notorious socioeconomic differences. The main health problems are acquired diseases related to sanitary conditions that affect mainly the large segment afflicted by poverty and extreme poverty. The state’s health policy does not contemplate any action on congenital or genetic conditions, and genetic ...
openaire +3 more sources
Molecular Oncology, EarlyView.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Genetics and Molecular Biology, 2014 Latin America and the Caribbean region make up one of the largest areas of the world, and this region is characterized by a complex mixture of ethnic groups sharing Iberian languages.
Augusto Rojas-Martínez +4 more
doaj +1 more source
Genie: A Secure, Transparent Sharing and Services Platform for Genetic and Health Data [PDF]
arXiv, 2018 Artificial Intelligence (AI) incorporating genetic and medical information have been applied in disease risk prediction, unveiling disease mechanism, and advancing therapeutics. However, AI training relies on highly sensitive and private data which significantly limit their applications and robustness evaluation.
arxiv
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source
Application of medical genetics in Turkey
The Turkish Journal of Pediatrics, 2007 Turkey is among the most populous countries of the world, and has a young population structure. The rate of consanguinity has been approximately 20-25% for the last 25 years. Various studies have shown that high consanguinity can be a contributing
Ergül Tunçbilek, Meral Ozgüç
doaj
Prompting Whole Slide Image Based Genetic Biomarker Prediction [PDF]
arXivPrediction of genetic biomarkers, e.g., microsatellite instability and BRAF in colorectal cancer is crucial for clinical decision making. In this paper, we propose a whole slide image (WSI) based genetic biomarker prediction method via prompting techniques.
arxiv
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Human Genetic Variation: A Flipped Classroom Exercise in Cultural Competency
MedEdPORTAL, 2013 Introduction Our understanding of human genetic variation has deepened through the Human Genome and International HapMap projects, which gave us a high-resolution view of human genetic variation and ancestry.
Shoumita Dasgupta, Katherine Tuttle
doaj +1 more source
Classification of Heart Disease Using K- Nearest Neighbor and Genetic Algorithm [PDF]
arXiv, 2015 Data mining techniques have been widely used to mine knowledgeable information from medical data bases. In data mining classification is a supervised learning that can be used to design models describing important data classes, where class attribute is involved in the construction of the classifier.
arxiv