Results 91 to 100 of about 1,151,409 (312)

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

A culture-independent approach to unravel uncultured bacteria and functional genes in a complex microbial community [PDF]

, 2012
Most microorganisms in nature are uncultured with unknown functionality. Sequence-based metagenomics alone answers 'who/what are there?' but not 'what are they doing and who is doing it and how?'.
Zhou, Q., Kalin, Robert M, Xu, Jian, Wang Yun, Huang, Wei E, Stephen Rolfe, Huang Wei E., Rolfe, Stephen A., Rolfe Stephen, Kang Ning, Huang Shi, Kalin, Robert M., Kalin, R.M., Robert M Kalin, Kalin Robert M., Xu, J., Huang, Shi, Yin Chen, Xu Jian, Shi Huang, Chen Yin, Chen, Y., Huang, S., Jian Xu (31545), Ning, Kang, Wei E. Huang (125868), Yin Chen (125855), Rolfe, Stephen, Yun Wang (32846), Qian Zhou, Jian Xu, Wei E Huang, Yun Wang, Ning, K., Chen, Yin, Zhou, Qian, Huang, W.E., Huang, Wei E., Stephen Rolfe (125866), Ning Kang, Shi Huang (125861), Wang, Yun, Wang, Y., Rolfe, S., Zhou Qian, Kang Ning (59789), Robert M. Kalin (125864), Qian Zhou (125859)   +47 more
core   +2 more sources

Unravelling Metagenomics Approach for Microbial Biofuel Production

, 2022
Renewable biofuels, such as biodiesel, bioethanol, and biobutanol, serve as long-term solutions to fossil fuel depletion. A sustainable approach feedstock for their production is plant biomass, which is degraded to sugars with the aid of microbes-derived
Leonidas Matsakas, Patel, Alok,, Alok Patel, Prasad, Ramasare, Km Sartaj, Matsakas, Leonidas,, Patel, Alok, Sartaj, Km,, Ramasare Prasad, Sartaj, Km, Matsakas, Leonidas, Prasad, Ramasare,   +11 more
core   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Lantibiotic production is a burden for the producing staphylococci

Scientific Reports, 2018
Lantibiotics are antimicrobial peptides that contain non-proteinogenic amino acids lanthionine and 3-methyllanthionine and are produced by Gram-positive bacteria.
Patrick Ebner, Sebastian Reichert, Arif Luqman, Bernhard Krismer, Peter Popella, Friedrich Götz   +5 more
doaj   +1 more source

NEW GENETICS, NEW IDENTITIES

, 2007
List of contributors -- Acknowledgements -- 1. Introduction: new genetic identities? / Paul Atkinson and Peter Glasner -- 2. Genetic advocacy groups, science and biovalue: creating political economies of hope / Carlos Novas -- 3.

core  

Genetics in clinical practice: general practitioners' educational priorities in European countries

, 2008
PURPOSE: To assess how general practitioners (GPs) from European countries prioritized their genetic educational needs according to their geographic, sociodemographic, and educational characteristics.
Schmidtke, Joerg, Kate, L. ten, Ulf Kristoffersson, Harris, H.J., Plass, A.M., Anne-Marie Plass, Kirsty Challen, Julian-Reynier, Claire, Calefato, Jean-Marc, Ten Kate, Leo, Kristoffersson, U., Harris, Rodney, ten Kate, L.P., Plass, Anne-Marie, Benjamin, Caroline, Anionwu, E., Calefato, J.M., Irma Nippert, Caroline Benjamin, Leo Ten Kate, Schmidtke, J., Challen, K., Anionwu, Elizabeth, Claire Julian-Reynier, Harris, R, Julian-Reynier, C., Joerg Schmidtke, Rodney Harris, Harris, R., Plass, A.M.C., Benjamin, C.M., Jean-Marc Calefato, Nippert, Irma, Nippert, I., Challen, Kirsty, Hilary Harris, Benjamin, C., Harris, Hilary, Kristoffersson, Ulf, Lund University., Elizabeth Anionwu, Kristoffersson, Ulf,   +41 more
core   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Strain Improvement and Microbial Biosynthesis

Recent industrial biotechnology developments have revealed the enormous potential of microbial fermentation as an alternative to the chemical syntheses of many valuable compounds [...
Penka Petrova, Kaloyan Petrov
core   +1 more source

Genetic dysbiosis: the role of microbial insults in chronic inflammatory diseases [PDF]

, 2014
Thousands of bacterial phylotypes colonise the human body and the host response to this bacterial challenge greatly influences our state of health or disease. The concept of infectogenomics highlights the importance of host genetic factors in determining
Syed Tariq Sadiq, Nibali, L, Luigi Nibali, Henderson, B, Sadiq, ST, Brian Henderson, Donos, N, Nikos Donos   +7 more
core   +2 more sources