Results 261 to 270 of about 1,219,858 (356)

Kinsenoside‐Loaded Microneedle Accelerates Diabetic Wound Healing by Reprogramming Macrophage Metabolism via Inhibiting IRE1α/XBP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu   +13 more
wiley   +1 more source

Gut microbiota diversity affects fish behaviour and is influenced by host genetics and early rearing conditions. [PDF]

open access: yesOpen Biol
Anka IZ   +6 more
europepmc   +1 more source

Mercaptophenylboronic Acid‐Mediated Nanozyme Immunochromatographic Assay for Simultaneous Detection of Respiratory Bacteria and Virus

open access: yesAdvanced Science, EarlyView.
This study developes a universal colorimetric ICA platform that integrates broad‐spectrum recognition by 4‐mercaptophenylboronic acid with dual signal enhancement—both colorimetric and catalytic—mediated by a biomimetic magnetic nanozyme. This platform, for the first time, enables simple, convenient, ultrasensitive, and simultaneous screening of ...
Qing Yu   +7 more
wiley   +1 more source

Mechanistic Foundations of KRAS‐Driven Tumor Ecosystems: Integrating Crosstalk among Immune, Metabolic, Microbial, and Stromal Microenvironment

open access: yesAdvanced Science, EarlyView.
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma   +9 more
wiley   +1 more source

Microbiome Research in Greece: A Comprehensive Bibliometric Study. [PDF]

open access: yesMicroorganisms
Stefanis C   +4 more
europepmc   +1 more source

Living Biotherapeutics Using Nanoparticles‐Armed Cyanobacteria for Boosting Photodynamic‐Immunotherapy of Cancer

open access: yesAdvanced Science, EarlyView.
A schematic illustration of the cyanobacteria‐based biohybrid platform for photodynamic cancer therapy enhanced PDT. The platform continuously outputs O2 (to alleviate tumor hypoxia) and 1O2 (for tumor treatment), achieving improved photodynamic immunotherapy. Abstract The interdisciplinary development of synthetic biology and material sciences propels
Zhengwei Xu   +14 more
wiley   +1 more source

In Situ Valence Engineering of Copper Silicate Nanozymes with Enhanced Peroxidase‐Like Catalytic Activity for Oral Disease Detection

open access: yesAdvanced Science, EarlyView.
A novel copper silicate nanozyme (CSHSs‐Ar) with high peroxidase‐like catalytic activity and great catalytic specificity is well developed using a facile in situ valence‐engineered approach. The well‐developed CSHSs‐Ar nanozyme‐involved system can be utilized and employed as an efficient colorimetric sensor for the detection of volatile sulfur ...
Xiaocan Liu   +9 more
wiley   +1 more source

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