Results 231 to 240 of about 7,649,767 (328)

First evaluation of genetic diversity and population structure of Phelsuma inexpectata (Gekkonidae), a critically endangered gecko endemic to Reunion Island. [PDF]

PLoS One
Gomard Y, Sanchez M, Caubit M, Roesch MA, Bonanno A, Clémencet J.   +5 more
europepmc   +1 more source

Multi‐Omics Integration for Advancing Glioma Precision Medicine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia, Valentina La Cognata, Giulia Gentile, Giovanna Morello, Sebastiano Cavallaro   +4 more
wiley   +1 more source

Human population genetics of the Mediterranean

Annals of Human Biology, 2018
David Comas, Donata Luiselli, Olga Rickards   +2 more
doaj   +1 more source

Simple scaling laws control the genetic architectures of human complex traits. [PDF]

PLoS Biol
Simons YB, Mostafavi H, Zhu H, Smith CJ, Pritchard JK, Sella G.   +5 more
europepmc   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Dental genomics in Africa: colonial legacies and research gaps. [PDF]

Front Oral Health
Kabbashi S, Roomaney IA, Chetty M.
europepmc   +1 more source

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma, Ilo Leppik, Thomas Henry, Thaddeus Walczak, Sima Patel, Robert McGovern   +5 more
wiley   +1 more source

Rare diseases load through the study of a regional population. [PDF]

PLoS Genet
Michel É, Moreau C, Gagnon L, Gagnon M, Leblanc J, Tardif J, Girard L, Mathieu J, Gagnon C, Desmeules M, Brisson JD, Bouchard L, Girard SL.   +12 more
europepmc   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

Threshold-Based Overlap of Breast Cancer High-Risk Classification Using Family History, Polygenic Risk Scores, and Traditional Risk Models in 180,398 Women. [PDF]

Cancers (Basel)
Ho PJ, Loo CKY, Lim RJY, Goh MH, Abubakar M, Ahearn TU, Andrulis IL, Antonenkova NN, Aronson KJ, Augustinsson A, Behrens S, Bodelon C, Bogdanova NV, Bolla MK, Brantley KD, Brenner H, Byers H, Camp NJ, Castelao JE, Cessna MH, Chang-Claude J, Chanock SJ, Chenevix-Trench G, Choi JY, Colonna SV, Czene K, Daly MB, Derouane F, Dörk T, Eliassen AH, Engel C, Eriksson M, Evans DG, Fletcher O, Fritschi L, Gago-Dominguez M, Genkinger JM, Geurts-Giele WRR, Glendon G, Hall P, Hamann U, Ho CYS, Ho WK, Hooning MJ, Hoppe R, Howell A, Humphreys K, Ito H, Iwasaki M, Jakubowska A, Jernström H, John EM, Johnson N, Kang D, Kim SW, Kitahara CM, Ko YD, Kraft P, Kwong A, Lambrechts D, Larsson S, Li S, Lindblom A, Linet M, Lissowska J, Lophatananon A, MacInnis RJ, Mannermaa A, Manoukian S, Margolin S, Matsuo K, Michailidou K, Milne RL, Mohd Taib NA, Muir KR, Murphy RA, Newman WG, O'Brien KM, Obi N, Olopade OI, Panayiotidis MI, Park SK, Park-Simon TW, Patel AV, Peterlongo P, Plaseska-Karanfilska D, Pylkäs K, Rashid MU, Rennert G, Rodriguez J, Saloustros E, Sandler DP, Sawyer EJ, Scott CG, Shahi S, Shu XO, Shulman K, Simard J, Southey MC, Stone J, Taylor JA, Teo SH, Teras LR, Terry MB, Torres D, Vachon CM, Houdt MV, Verhoeven J, Weinberg CR, Wolk A, Yamaji T, Yip CH, Zheng W, Hartman M, Li J, On Behalf Of The Abctb Investigators, kConFab Investigators, MyBrCa Investigators, Sgbcc Investigators.   +118 more
europepmc   +1 more source