Results 1 to 10 of about 616,975 (266)
Author Correction: Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes
Nature Communications, 2021 A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21077-8.
Qingbo Wang +11 more
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The population genetics of dN/dS. [PDF]
PLoS Genetics, 2008 Evolutionary pressures on proteins are often quantified by the ratio of substitution rates at non-synonymous and synonymous sites. The dN/dS ratio was originally developed for application to distantly diverged sequences, the differences among which ...
Sergey Kryazhimskiy, Joshua B Plotkin
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Information-Geometric Optimization with Natural Selection
Entropy, 2020 Evolutionary algorithms, inspired by natural evolution, aim to optimize difficult objective functions without computing derivatives. Here we detail the relationship between classical population genetics of quantitative traits and evolutionary ...
Jakub Otwinowski +2 more
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Archetypal Analysis for population genetics.
PLoS Computational Biology, 2022 The estimation of genetic clusters using genomic data has application from genome-wide association studies (GWAS) to demographic history to polygenic risk scores (PRS) and is expected to play an important role in the analyses of increasingly diverse ...
Julia Gimbernat-Mayol +4 more
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Population-Matched Transcriptome Prediction Increases TWAS Discovery and Replication Rate
iScience, 2020 Summary: Most genome-wide association studies (GWAS) and transcriptome-wide association studies (TWAS) focus on European populations; however, these results cannot always be accurately applied to non-European populations due to genetic architecture ...
Elyse Geoffroy +2 more
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Annual Review of Genetics, 1967 Uploaded by Plazi for TaxoDros. We do not have abstracts.
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Molecular Population Genetics [PDF]
Genetics, 2017 AbstractMolecular population genetics aims to explain genetic variation and molecular evolution from population genetics principles. The field was born 50 years ago with the first measures of genetic variation in allozyme loci, continued with the nucleotide sequencing era, and is currently in the era of population genomics.
Casillas Viladerrams, Sònia|| +1 more
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Population genetics in microchannels
Proceedings of the National Academy of Sciences, 2022 Significance Many microbial populations proliferate in small channels. In such environments, reproducing cells organize in parallel lanes. Reproducing cells shift these lanes, potentially expelling other cells from the channel.
Anzhelika Koldaeva +3 more
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Pedigree Analysis: A Team-Based Learning Activity
MedEdPORTAL, 2017 Introduction Regardless of their specialty, physicians, particularly those practicing primary care in rural areas, typically encounter genetic conditions.
Jack Thatcher +3 more
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Scientific Reports, 2022 Non-invasive prenatal testing (NIPT) to detect fetal aneuploidy by sequencing the cell-free DNA (cfDNA) in maternal plasma is being broadly adopted. To detect fetal aneuploidies from maternal plasma, where fetal DNA is mixed with far-larger amounts of ...
Giulio Genovese +7 more
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