Results 231 to 240 of about 6,085,254 (274)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Knowledge, attitudes, and self-efficacy toward cancer genetic testing among Black women with and without breast cancer. [PDF]

Cancer Causes Control
Bertrand KA, Trevino-Talbot M, Ruderman M, Flynn M, Cabral HJ, Palmer JR, Wang C.   +6 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Reply of the authors: "Do children born after embryo vitrification differ from siblings born after fresh embryo transfer?" [PDF]

F S Rep
Belva F, De Schepper J, Blockeel C.
europepmc   +1 more source

Advancing genomic medicine in Nigeria: research progress, clinical translation and policy priorities. [PDF]

J Community Genet
Abdullateef RO, Olawuyi DA, Usin SG, Olajire GA, Opatola AD, Agboola RA, Ibrahim GZ.   +6 more
europepmc   +1 more source

Revisiting additive and dominance effects. [PDF]

G3 (Bethesda)
Endelman JB, Dawson JC.
europepmc   +1 more source

Dynamism under the hood: Coevolutionary maintenance of variation in hosts and parasites. [PDF]

PLoS Biol
Graham AL, Chang van Oordt DA.
europepmc   +1 more source