Results 91 to 100 of about 2,771,911 (398)

Prenatal Screening and Genetics [PDF]

open access: yes, 2001
Although the term 'genetic screening' has been used for decades, this paper discusses how, in its most precise meaning, genetic screening has not yet been widely introduced. 'Prenatal screening' is often confused with 'genetic screening'.
Alderson, Priscilla   +7 more
core   +4 more sources

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

Correction: Transcription Factors Encoded on Core and Accessory Chromosomes of Fusarium oxysporum Induce Expression of Effector Genes. [PDF]

open access: yesPLoS Genetics, 2016
[This corrects the article DOI: 10.1371/journal.pgen.1006401.].
PLOS Genetics Staff
doaj   +1 more source

Computing vs. Genetics [PDF]

open access: yes, 2009
This chapter first presents the interrelations between computing and genetics, which both are based on information and, particularly, self-reproducing artificial systems. It goes on to examine genetic code from a computational viewpoint.
Barreiro Sorrivas, Jose Maria   +1 more
core   +1 more source

Joint and individual analysis of breast cancer histologic images and genomic covariates [PDF]

open access: yes, 2020
A key challenge in modern data analysis is understanding connections between complex and differing modalities of data. For example, two of the main approaches to the study of breast cancer are histopathology (analyzing visual characteristics of tumors ...
Calhoun, Benjamin C.   +10 more
core   +3 more sources

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

Stability and response of polygenic traits to stabilizing selection and mutation

open access: yes, 2014
When polygenic traits are under stabilizing selection, many different combinations of alleles allow close adaptation to the optimum. If alleles have equal effects, all combinations that result in the same deviation from the optimum are equivalent ...
Barton   +8 more
core   +1 more source

Biochemical Aspects of Genetics [PDF]

open access: yes, 1965
It would be impossible, in the time and space available, to cover all of the noteworthy advances that have been made in biochemical genetics during the past year.
Horowitz, N. H., Metzenberg, Robert L.
core   +1 more source

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

open access: yesFEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang   +9 more
wiley   +1 more source

Effects of Genetics and Environment on Red Flour Beetle Aggregation [PDF]

open access: yes, 2018
Red Flour Beetles are major pests for farmers storing grain and cause large profit losses. These beetles infest grain stores and their presence leads to mold growth (Baldwin).
Marshall, Jeremy, Toothaker, J. E.
core  

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