Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Expression of Concern: Protein Under-Wrapping Causes Dosage Sensitivity and Decreases Gene Duplicability. [PDF]
PLoS Genetics, 2015 PLOS Genetics Editors
doaj +1 more source
Two Decades of Optogenetic Tools: A Retrospective and a Look Ahead (Advanced Genetics 3/06). [PDF]
Adv Genet (Hoboken)Duan X, Zhu M, Gao S.
europepmc +1 more source
GENETICS OF NATURAL POPULATIONS. XVI. ALTITUDINAL AND SEASONAL CHANGES PRODUCED BY NATURAL SELECTION IN CERTAIN POPULATIONS OF DROSOPHILA PSEUDOOBSCURA AND DROSOPHILA PERSIMILIS [PDF]
, 1948 Theodosius Dobzhansky
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Correction: Genetic Mechanism of Human Neutrophil Antigen 2 Deficiency and Expression Variations. [PDF]
PLoS Genetics, 2015 PLOS Genetics Staff
doaj +1 more source
THE GENETICS OF SCHIZOPHYLLUM COMMUNE [PDF]
, 1958 John R. Raper, Philip G. Miles
openalex +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Correction: Genomic Location of the Major Ribosomal Protein Gene Locus Determines Vibrio cholerae Global Growth and Infectivity. [PDF]
PLoS Genetics, 2015 PLOS Genetics Staff
doaj +1 more source
Intragenic <i>TTN</i> Deletions in a Single Family with Dilated Cardiomyopathy. [PDF]
Appl Clin GenetWayhelova M +5 more
europepmc +1 more source