Results 191 to 200 of about 1,386,700 (294)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Patient-Reported Outcomes From Males Regarding Germline Testing for Prostate Cancer: Results From the PROGRESS Registry. [PDF]

JCO Precis Oncol
Loeb S, Keith SW, Gross L, Hartman RL, Beer TM, Brierley KL, Cheng HH, Couvillon A, Dicker AP, Friedman S, Gomella LG, Karsh L, Kelly WK, Lallas CD, Leader AE, Mann MJ, Mark JR, Mille P, Paller CJ, Rana HQ, Sokolova AO, Trabulsi EJ, Whang YE, Giri VN.   +23 more
europepmc   +1 more source

DISTRIBUTION AND GENETICS OF THE COLOR PHASES OF THE RED FOX IN CANADA [PDF]

, 1945
L. Butler
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Editorial Note: PHYTOCHROME C regulation of photoperiodic flowering via PHOTOPERIOD1 is mediated by EARLY FLOWERING 3 in Brachypodium distachyon.

PLoS Genetics
PLOS Genetics Editors
doaj   +1 more source

Cyto-genetics in Relation to Sugarcane Breeding

, 1954
T. S. Raghavan
openalex   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Comprehensive Bibliometric Assessment of the Top 50 Cited Articles on Osteogenesis Imperfecta. [PDF]

Orthop Rev (Pavia)
Alanazi AS, Alshehri AF, Alnowaishiri KA, Al-Hajri JS, Rifadah KA, Alanazi BK, AlGhufaynah MM, Aldossari AM.   +7 more
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Development and psychometric evaluation of a new genetic attitudes questionnaire in two national samples of United States residents. [PDF]

Sci Rep
Ksiazkiewicz A, Jung S, Schneider S, Qian J, Betchley J, Gunter CA.   +5 more
europepmc   +1 more source