Results 211 to 220 of about 1,730,988 (338)

P3–018: NIA genetics of Alzheimer's disease data storage site (NIAGADS): 2013 update [PDF]

open access: bronze, 2013
Chiao‐Feng Lin   +8 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Genetics Adviser: The development and usability testing of a new patient digital health application to support clinical genomic testing

open access: diamond
Marc Clausen   +28 more
openalex   +1 more source

Human Genetics Shape the Gut Microbiome

open access: yesCell, 2014
Julia Goodrich   +12 more
semanticscholar   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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