Results 241 to 250 of about 3,105,692 (378)

Correction: Altered Ca2+ Kinetics Associated with α-Actinin-3 Deficiency May Explain Positive Selection for ACTN3 Null Allele in Human Evolution. [PDF]

PLoS Genetics, 2015
PLOS Genetics Staff
doaj   +1 more source

Human Genetics Shape the Gut Microbiome

Cell, 2014
Julia Goodrich, Jillian L. Waters, Angela C. Poole, Jessica L. Sutter, O. Koren, R. Blekhman, M. Beaumont, W. V. Treuren, R. Knight, J. Bell, T. Spector, A. Clark, R. Ley   +12 more
semanticscholar   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Microbial Biofilms: from Ecology to Molecular Genetics

Microbiology and Molecular Biology Reviews, 2000
M. E. Davey, G. O’Toole
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Utilization of genomic services among physicians in Kenya. [PDF]

PLoS One
Sigilai H, Ogola E, Ilovi S.
europepmc   +1 more source

Stroke Risk Factors, Genetics, and Prevention

Circulation Research, 2017
A. Boehme, Charles C. Esenwa, M. Elkind
semanticscholar   +1 more source

Genetics of Thyroid-Stimulating Hormone Receptor—Relevance for Autoimmune Thyroid Disease [PDF]

, 2017
Mihaela Stefan, Larissa C. Faustino
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Consent, Concern, and Capacity: Factors Associated With Attitudes Toward Pharmacogenetic Testing Among Patients With Gastrointestinal Cancer. [PDF]

Clin Transl Sci
Anantharajah A, Chaudhry R, Wittner VA, Cayabyab MAS, Hoffecker G, Wang X, Conway LJ, Medicine Biobank P, Teitelbaum UR, Tuteja S.   +9 more
europepmc   +1 more source