Correction: ALIX and ESCRT-III Coordinately Control Cytokinetic Abscission during Germline Stem Cell Division In Vivo. [PDF]
PLOS Genetics Staff
doaj +1 more source
THE GENETICS OF CONGENITAL HEART DISEASE AND SITUS INVERSUS IN SIBS [PDF]
M. Campbell
openalex +1 more source
Stroke Risk Factors, Genetics, and Prevention
A. Boehme, Charles C. Esenwa, M. Elkind
semanticscholar +1 more source
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Correction: CAPER Is Vital for Energy and Redox Homeostasis by Integrating Glucose-Induced Mitochondrial Functions via ERR-α-Gabpa and Stress-Induced Adaptive Responses via NF-κB-cMYC. [PDF]
PLOS Genetics Staff
doaj +1 more source
The impact of a mainstream genetic testing pathway and socioeconomic factors on the uptake of germline genetic testing in breast cancer patients: results of the nationwide GENE-SMART study. [PDF]
Jong CL+4 more
europepmc +1 more source
STUDIES ON THE GENETICS OF ANTIBIOTIC FORMATION: THE INDUCTION OF ANTIBIOTIC-FORMING MUTANTS IN ACTINOMYCETES [PDF]
Albert Kelner
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Decoding RNA-Protein Interactions: Methodological Advances and Emerging Challenges (Advanced Genetics 2/06). [PDF]
Yi W, Yan J.
europepmc +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source