Results 181 to 190 of about 640,355 (344)

Editorial: Restoration genetics and genomics

Frontiers in Conservation Science
Arne Ludwig, Arne Ludwig, Daniel W. Foerster   +2 more
doaj   +1 more source

Genetics and Genomics in Sickle Cell Disease in Africa. [PDF]

Am J Hematol
Nkya S, Makani J, Flanagan JM.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Evaluation of the Integration of Genetics and Genomics Into Nursing Practice. [PDF]

J Nurs Scholarsh
Calzone K, Stokes L, Peterson C, Yee LM, Liewehr D, Badzek L.   +5 more
europepmc   +1 more source

State-of-the-Art Molecular Genetics and Genomics in Germany. [PDF]

Int J Mol Sci, 2023
Lukas J.
europepmc   +1 more source

Genetic evaluation of cardiomyopathy: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG)

Genetics in Medicine, 2018
R. Hershberger, M. Givertz, Carolyn Y. Ho, D. Judge, P. Kantor, K. McBride, A. Morales, Matthew R. G. Taylor, M. Vatta, S. Ware, on behalf of the Acmg Laboratory Quality Assurance Committee   +10 more
semanticscholar   +1 more source

Points to consider for reporting of germline variation in patients undergoing tumor testing: a statement of the American College of Medical Genetics and Genomics (ACMG)

Genetics in Medicine, 2020
Marilyn M. Li, E. Chao, E. Esplin, David T. Miller, K. Nathanson, S. Plon, M. Scheuner, D. Stewart, Acmg Professional Practice and Guidelines Committee   +8 more
semanticscholar   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Genetics and Genomics of Pediatric Neurological Disorders: An Overview of Current Insights and Future Directions. [PDF]

Genes (Basel)
Trabacca A, De Rinaldis M, Oliva MC, Notaristefano I, Gallo I, Ferrante C, Fanizza I.   +6 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source