Results 171 to 180 of about 343,001 (303)

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

PROTOCOL: Utilisation of Genetics and Genomics in Primary Care: Protocol for an Evidence and Gap Map. [PDF]

Campbell Syst Rev
Valencia BM, Lin J, Chomik R, Dietz C, Bates S, Brown P, Mao L, Davidson PM, Wilkins MR, Martiniuk A, Kidd M, Keshri VR.   +11 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Health Disparities in Genomics and Genetics

Nursing Research and Practice, 2014
Ida J. Spruill, Jacquelyn Taylor, Irma B. Ancheta, Adebowale A. Adeyemo, Yolanda Powell-Young, Willa Doswell   +5 more
doaj   +1 more source

NEW GENETICS, NEW SOCIAL FORMATIONS

, 2007
List of illustrations -- Contributors -- Acknowledgements -- 1. Introduction: new genetics, new social formations / Peter Glasner and Paul Atkinson -- 2. British public attitudes to agricultural biotechnology and the 2003 GM Nation?

core  

Editorial: Exploring the intersection of animal breeding, genetics, and genomics in modern agriculture. [PDF]

Front Genet
Davenport KM, Estrada-Reyes ZM, Wilson CS.   +2 more
europepmc   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Evaluation of the Integration of Genetics and Genomics Into Nursing Practice. [PDF]

J Nurs Scholarsh
Calzone K, Stokes L, Peterson C, Yee LM, Liewehr D, Badzek L.   +5 more
europepmc   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Nurses' Genomic Knowledge, Attitudes, and Perceived Organizational Support: A Comparative Secondary Analysis of Genetics and Genomics in Nursing Practice Survey Data. [PDF]

J Nurs Scholarsh
Yesilcinar I, Laaksonen M, Halkoaho A, Calzone K, Limoges J.   +4 more
europepmc   +1 more source