Results 111 to 120 of about 688,262 (355)

Clinical Genetics in the age of Genomics and Genome editing [PDF]

, 2015
Reiner A. Veitia
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Genetics and clinical correlation of Dravet syndrome and its mimics – experience of a tertiary center in Taiwan

, 2021
Yi-Hsuan Liu, Yi-Ting Cheng, Meng‐Han Tsai, I‐Jun Chou, Po‐Cheng Hung, Meng‐Ying Hsieh, Yishan Wang, Yun‐Ju Chen, Cheng‐Yen Kuo, Jainn‐Jim Lin, Huei-Shyong Wang, Kuang‐Lin Lin   +11 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circulating biomarkers of kidney angiomyolipoma and cysts in tuberous sclerosis complex patients

iScience
Summary: Patients with tuberous sclerosis complex (TSC) develop multi-organ disease manifestations, with kidney angiomyolipomas (AML) and cysts being one of the most common and deadly.
Varvara I. Rubtsova, Yujin Chun, Joohwan Kim, Cuauhtemoc B. Ramirez, Sunhee Jung, Wonsuk Choi, Miranda E. Kelly, Miranda L. Lopez, Elizabeth Cassidy, Gabrielle Rushing, Dean J. Aguiar, Wei Ling Lau, Rebecca S. Ahdoot, Moyra Smith, Aimee L. Edinger, Sang-Guk Lee, Cholsoon Jang, Gina Lee   +17 more
doaj   +1 more source

BOOK REVIEWS: Familial Alzheimer's Disease. Molecular Genetics and Clinical Perspectives. (Neurological Disease and Therapy Series/2). [PDF]

, 1990
Martin N. Rossor
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Co-design of patient information leaflets for germline predisposition to cancer: recommendations for clinical practice from the UK Cancer Genetics Group (UKCGG), Cancer Research UK (CRUK) funded CanGene-CanVar Programme and the Association of Genetic Nurse Counsellors (AGNC) [PDF]

, 2023
Kelly Kohut, Beverley Speight, Julie Young, Rosalind Way, Jennifer Wiggins, Laura Monje‐Garcia, Diana Eccles, Claire Foster, Lesley Turner, Katie Snape, Helen Hanson, on behalf of the CanGene-CanVar Patient Reference Panel   +11 more
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Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Genetic and clinical characteristics of genetic tumor syndromes in the central nervous system cancers: Implications for clinical practice

iScience
Summary: Recognizing individuals with Genetic tumor syndromes (GTS) in the primary central nervous system (CNS) tumors is crucial for optimizing proper genetic counseling and improving therapeutics and clinical care.
Chuanwei Wang, Jian Chen, Yanzhao Wang, Ningning Luo, Tiantian Han, Xiangyu Yin, Yunjie Song, Dongsheng Chen, Jie Gong   +8 more
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Primary hypertrophic osteoarthropathy: genetics, clinical features and management. [PDF]

Front Endocrinol (Lausanne), 2023
Lu Q, Xu Y, Zhang Z, Li S, Zhang Z.
europepmc   +1 more source

Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease [PDF]

, 2016
Floris Imhann, Arnau Vich Vila, Marc Jan Bonder, Jingyuan Fu, Dirk Gevers, Marijn C. Visschedijk, Lieke M. Spekhorst, Rudi Alberts, Lude Franke, Hendrik M. van Dullemen, Rinze W. F. ter Steege, Curtis Huttenhower, Gerard Dijkstra, Ramnik J. Xavier, Eleonora A. Festen, Cisca Wijmenga, Alexandra Zhernakova, Rinse K. Weersma   +17 more
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